Triggers of mania and depression in young adults with bipolar disorder
Triggers of mania and depression in young adults with bipolar disorder
复制标题
DOI：
10.1016/j.jad.2012.05.052
复制
发表时间：
2012-12-20
影响因子：
6.6
通讯作者：
Delmas, Kristy
中科院分区：
文献类型：
--
作者：
Proudfoot, Judith;Whitton, Alexis;Delmas, Kristy
背景：早期干预可显著降低双相情感障碍的影响。然而，很少有研究调查触发因素，可能是躁狂/轻躁狂发作的独特沉淀物，以及这些触发因素与双相抑郁症的特定触发因素有何不同。方法：被诊断患有双相情感障碍的18至30岁的个体（n=198）完成了一项在线调查，以确定躁狂/轻躁狂和抑郁症的独特触发因素，以及两者共同的触发点受访者评价了一系列情况和行为在过去促成躁狂/轻躁狂发作或抑郁发作的频率。调查数据进行了补充，深入的面对面访谈（n=11）。结果：触发具体与躁狂/轻躁狂发作包括坠入爱河，娱乐兴奋剂的使用，开始一个创造性的项目，深夜聚会，去度假，听大声的音乐。与抑郁发作相关的触发因素包括压力性生活事件、一般压力、疲劳、睡眠剥夺、身体伤害或疾病、月经和体育锻炼减少。另一组触发因素被确定为躁狂/轻躁狂和抑郁发作的共同点。一致的主题出现从分析的面对面的访谈，扩展和照明的调查结果的data.Conclusions：识别一组独特的触发躁狂/轻躁狂和一组独特的抑郁症的年轻人与双相情感障碍可以允许早期识别的发作，从而增加早期干预的机会。(C)2012 Elsevier B. V.保留所有权利。
Background: Early intervention significantly decreases the impact of bipolar disorder. However, there is little research investigating triggers that may be unique precipitants of manic/hypomanic episodes, and how these may differ from triggers specific to bipolar depression, in young adults with the disorder.Methods: Individuals aged 18 to 30 years who had been diagnosed with bipolar disorder (n=198) completed an online survey to identify triggers unique to mania/hypomania and depression, as well as triggers which were common to both. Respondents rated how frequently a series of situations and behaviours had precipitated either a manic/hypomanic episode or a depressive episode in the past. Survey data was supplemented by in-depth face-to-face interviews (n=11).Results: Triggers specifically associated with the onset of manic/hypomanic episodes included falling in love, recreational stimulant use, starting a creative project, late night partying, going on vacation and listening to loud music. Triggers associated with depressive episodes included stressful life events, general stress, fatigue, sleep deprivation, physical injury or illness, menstruation and decreases in physical exercise. A further set of triggers were identified as being common to both manic/hypomanic and depressive episodes. Consistent themes arose from the analysis of face-to-face interviews, which extended and illuminated the findings of the survey data.Conclusions: Identification of a unique set of triggers for mania/hypomania and a unique set for depression in young adults with bipolar disorder may allow for earlier identification of episodes, thus increasing opportunities for early intervention. (C) 2012 Elsevier B.V. All rights reserved.