An fMRI study of verbal self-monitoring:: Neural correlates of auditory verbal feedback
An fMRI study of verbal self-monitoring:: Neural correlates of auditory verbal feedback
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DOI：
10.1093/cercor/bhj039
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发表时间：
2006-07-01
期刊：
影响因子：
3.7
通讯作者：
McGuire, Philip K.
中科院分区：
文献类型：
--
作者：
Fu, Cynthia H. Y.;Vythelingum, Goparlen N.;McGuire, Philip K.
识别自己内心言语的能力对于自我意识至关重要。言语自我监控模型提出，这个过程需要从参与言语产生的神经区域到言语感知区域的沟通。根据该模型，如果预期的言语反馈与感知的反馈相匹配，那么外侧颞叶皮层的激活就不会发生变化。我们在功能磁共振（fMRI）研究中研究了言语自我监控的神经相关性。十三名健康的男性志愿者大声朗读所呈现的形容词，并听到他们经过实验修改的听觉反馈。关于反馈来源的决定是通过按下按钮响应做出的。我们使用了“集群”功能磁共振成像采集序列，包括相对安静的时期，受试者可以在没有扫描仪噪音的情况下大声说话并听到反馈，以及事件相关的设计，允许对与正确归因和错误归因相关的试验进行单独分析。当反馈是他们声音的扭曲版本时，受试者会做出更多的错误归因反应。相对于听到自己未失真的声音和听到另一个人的声音的情况，这种情况显示出更高的时间激活。此外，在这种情况下，正确的归因比错误归因与更大的时间激活相关。这些发现支持自我监控模型，因为预期和实际听觉反馈之间的不匹配与更大的时间激活相关。
The ability to recognize one's own inner speech is essential for a sense of self. The verbal self-monitoring model proposes that this process entails a communication from neural regions involved in speech production to areas of speech perception. According to the model, if the expected verbal feedback matches the perceived feedback, then there would be no change in activation in the lateral temporal cortices. We investigated the neural correlates of verbal self-monitoring in a functional magnetic resonance (fMRI) study. Thirteen healthy male volunteers read aloud presented adjectives and heard their auditory feedback which was experimentally modified. Decisions about the source of the feedback were made with a button-press response. We used a 'clustered' fMRI acquisition sequence, consisting of periods of relative silence in which subjects could speak aloud and hear the feedback in the absence of scanner noise, and an event-related design which allowed separate analysis of trials associated with correct attributions and misattributions. Subjects made more misattribution responses when the feedback was a distorted version of their voice. This condition showed increased superior temporal activation relative to the conditions of hearing their own voice undistorted and hearing another person's voice. Furthermore, correct attributions during this condition were associated with greater temporal activation than misattributions. These findings support the self-monitoring model as mismatches between expected and actual auditory feedback were associated with greater temporal activation.