Effect of recombinant human erythropoietin on the switchover from fetal to adult hemoglobin synthesis in preterm infants.
Effect of recombinant human erythropoietin on the switchover from fetal to adult hemoglobin synthesis in preterm infants.
复制标题
重组人促红细胞生成素对早产儿从胎儿血红蛋白合成到成人血红蛋白合成的转换的影响。
DOI：
10.1016/s0022-3476(95)70086-2
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Widness,JA
中科院分区：
文献类型：
--
作者：
Bard,H;Widness,JA
为了确定给予极低出生体重儿重组促红细胞生成素（r-HuEpo）是否能增加血红蛋白F的合成，或延缓其发育程序性下降，我们连续测定了15例接受安慰剂或r-HuEpo的早产儿血红蛋白A和F的合成。两组间血红蛋白F合成比例与孕后年龄无差异。（J PediATR 1995;127：478-80）
To determine whether recombinant erythropoietin (r-HuEpo) administered to very low birth weight infants could increase hemoglobin F synthesis, or delay its developmentally programmed decline, we determined serially the synthesis of hemoglobins A and F in 15 preterm infants receiving either a placebo or r-HuEpo. There was no difference between the two groups in the proportion of hemoglobin F being synthesized in relation to postconceptional age. (J PEDIATR 1995;127:478-80)