Pegylated Interferon Alpha‐2b for Patients with HCV Recurrence and Graft Fibrosis Following Liver Transplantation

Pegylated Interferon Alpha‐2b for Patients with HCV Recurrence and Graft Fibrosis Following Liver Transplantation
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聚乙二醇干扰素α-2b治疗肝移植后HCV复发和移植物纤维化患者

DOI:
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发表时间:
2006
影响因子:
8.8
通讯作者:
D. Mutimer
D. Mutimer
中科院分区:
医学2区
文献类型:
--
作者:
M. Heydtmann;D. Freshwater;T. Dudley;V. Lai;S. Palmer;S. Hubscher;D. Mutimer

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慢性丙型肝炎是肝移植的主要指征。复发性病毒感染是不可避免的,移植物疾病是常见的。我们报告了聚乙二醇干扰素α 2b(PEG-IFN)单药治疗肝移植后丙型肝炎病毒(HCV)复发和纤维化患者的耐受性、安全性和有效性。血清HCV滴度的重复测量允许对所有患者的抗病毒反应的动力学进行评估。
Chronic hepatitis C is a principal indication for liver transplantation. Recurrent viral infection is inevitable and graft disease is common. We report tolerability, safety and efficacy of pegylated interferon alpha 2b (PEG‐IFN) monotherapy for patients with hepatitis C virus (HCV) recurrence and fibrosis after liver transplantation. Repeated measurements of serum HCV titer permitted assessment of the kinetics of the antiviral response for all patients.
DOI: 10.1086/315661
发表时间: 2000-07-01
影响因子: 6.4
作者:
Neumann, AU;Lam, NP;Layden, TJ
通讯作者: Layden, TJ
DOI: 10.1002/hep.1840200402
发表时间: 1994
期刊: Hepatology (Baltimore, Md.)
影响因子: --
作者:
Wright,TL;Combs,C;Kim,M;Ferrell,L;Bacchetti,P;Ascher,N;Roberts,J;Wilber,J;Sheridan,P;Urdea,M
通讯作者: Urdea,M