Roles of small RNAs in crop disease resistance.

Roles of small RNAs in crop disease resistance.
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小RNA在作物抗病性中的作用

DOI:
10.1007/s44154-021-00005-2
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发表时间:
2021-08-18
期刊:
Stress biology
影响因子:
--
通讯作者:
He, Zuhua
He, Zuhua
中科院分区:
其他
文献类型:
--
作者:
Tang, Jun;Gu, Xueting;Liu, Junzhong;He, Zuhua

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小rna (sRNAs)是一类短的非编码调控rna,已成为跨植物王国防御调控网络的关键组成部分。许多基于srna的技术,如宿主诱导的基因沉默(HIGS)、喷雾诱导的基因沉默(SIGS)、病毒诱导的基因沉默(VIGS)、人工微RNA (amiRNA)和合成反式siRNA (syn-tasiRNA)介导的RNA干扰(RNAi),已经发展成为单株和双株植物,特别是作物的疾病控制策略。这篇综述旨在强调我们目前对包括mirna、异色sirna (hc- sirna)、phasiRNAs、secondary sirna (phasiRNAs)和天然反义sirna (nat- sirna)在内的sRNAs在作物抗病性中的作用的理解,以及sRNAs介导的防御和生长之间的权衡。我们特别关注sRNAs在作物对细菌和真菌病原体、卵菌和病毒的防御反应中的多种功能。此外,我们重点介绍了基于srna的技术在保护作物免受病原体侵害方面的应用。提出了进一步的研究前景,以开发新的基于srnas的高效策略来培育非转基因、抗病作物,促进可持续农业。
Small RNAs (sRNAs) are a class of short, non-coding regulatory RNAs that have emerged as critical components of defense regulatory networks across plant kingdoms. Many sRNA-based technologies, such as host-induced gene silencing (HIGS), spray-induced gene silencing (SIGS), virus-induced gene silencing (VIGS), artificial microRNA (amiRNA) and synthetic trans-acting siRNA (syn-tasiRNA)-mediated RNA interference (RNAi), have been developed as disease control strategies in both monocot and dicot plants, particularly in crops. This review aims to highlight our current understanding of the roles of sRNAs including miRNAs, heterochromatic siRNAs (hc-siRNAs), phased, secondary siRNAs (phasiRNAs) and natural antisense siRNAs (nat-siRNAs) in disease resistance, and sRNAs-mediated trade-offs between defense and growth in crops. In particular, we focus on the diverse functions of sRNAs in defense responses to bacterial and fungal pathogens, oomycete and virus in crops. Further, we highlight the application of sRNA-based technologies in protecting crops from pathogens. Further research perspectives are proposed to develop new sRNAs-based efficient strategies to breed non-genetically modified (GMO), disease-tolerant crops for sustainable agriculture.
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