Activity of cell immune response and open field behavior in Wistar and OXYS rats

Activity of cell immune response and open field behavior in Wistar and OXYS rats
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DOI:
10.1023/b:bebm.0000010957.87077.ae
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发表时间:
2003-10-01
影响因子:
0.7
通讯作者:
Kolosova, NG
Kolosova, NG
中科院分区:
医学4区
文献类型:
--
作者:
Markova, EV;Obukhova, LA;Kolosova, NG

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比较了Wistar和OXYS大鼠(早衰)的胸腺状态、细胞介导的免疫活性和旷场行为。在OXYS大鼠中发现胸腺早期退化,其形态学变化类型对应于意外退化,并与低水平的迟发型超敏反应以及运动和探索行为减少相关。
The state of the thymus, activity of cell-mediated immunity, and open field behavior were compared in Wistar and OXYS rats (premature aging). Early involution of the thymus was revealed in OXYS rats, which by the type of morphological changes corresponded to accidental involution and was associated with low level of delayed hypersensitivity reaction and decreased motor and exploratory behavior.