Comparison of cloned rabbit and mouse β-globin genes showing strong evolutionary divergence of two homologous pairs of introns
Comparison of cloned rabbit and mouse β-globin genes showing strong evolutionary divergence of two homologous pairs of introns
复制标题
克隆的兔和小鼠 β-珠蛋白基因的比较显示两个同源内含子对的强烈进化分歧
作者：
J. Berg;A. Ooyen;N. Mantei;A. Schamboeck;G. Grosveld;R. Flavell;C. Weissmann
克隆的小鼠和兔的β-珠蛋白基因均包含一个大小相等的插入序列（内含子），位于相对于编码序列精确相同的位置。同源内含子显示出一定的序列相似性，特别是在与编码序列的连接处。它们很可能起源于一个共同的祖先序列，并在进化过程中发生了很大的分歧。
Cloned β-globin genes of both mouse and rabbit each contain a large and a small intervening sequence (intron) of about equal length at precisely the same positions relative to the coding sequence. The homologous introns show some sequence similarity, particularly at the junctions with the coding sequence. They most probably arose from a common ancestral sequence and diverged substantially during evolution.