EFFECT OF AN ANION EXCHANGE RESIN ON SERUM CHOLESTEROL IN MAN
EFFECT OF AN ANION EXCHANGE RESIN ON SERUM CHOLESTEROL IN MAN
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DOI：
10.3181/00379727-102-25358
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发表时间：
1959-01-01
影响因子：
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通讯作者：
SEBRELL, WH
中科院分区：
文献类型：
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作者：
BERGEN, SS;VANITALLIE, TB;SEBRELL, WH
本文报告了一种具有胆汁酸螯合性能的树脂的初步结果。26名患者服用该制剂2至34周。26例患者中有23例血清总胆固醇水平降低超过10%。所有受试者的血清总胆固醇平均降低20%（p< 0.001）。未观察到全身副作用。6例接受6周或更长时间治疗的受试者保持血清总胆固醇值降低，无逃逸。
Preliminary results of administering a resin with bile acid-sequestering properties are reported. The preparation was administered to 26 patients for periods of 2 to 34 weeks. Serum total cholesterol levels were lowered by more than 10% in 23 of 26 patients. Average decrease in serum total cholesterol for all subjects was 20% (p< 0.001). No systemic side-effects were observed. Six subjects treated for 6 weeks or longer maintained lowered values of serum total cholesterol without escape.