Sebaceous Carcinoma Arising in Nevus Sebaceus
Sebaceous Carcinoma Arising in Nevus Sebaceus
复制标题
皮脂腺痣引起的皮脂癌
DOI：
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
M. Kakibuchi
中科院分区：
文献类型：
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作者：
K. Matsuda;T. Doi;H. Kosaka;N. Tasaki;H. Yoshioka;M. Kakibuchi
一名53岁的女性从出生起右脸颊和颈部就有一个淡棕色的病变。从她40岁左右开始，部分病变逐渐抬高，尺寸逐渐增大。第一次检查时，右脸颊上有一个110 × 70 × 35 mm的巨大肿块。进行了广泛的局部切除术，包括浅表腮腺切除术和颌下淋巴结清扫术，然后进行全层皮肤移植。肿瘤的组织学检查显示侵袭性真皮肿瘤，特征为由苏丹红IV染色的泡沫细胞组成的小叶与许多非典型细胞混合，显示其细胞核的形状和大小存在显著差异。周围上皮改变与皮脂痣一致。从这些发现，巨大的肿瘤被诊断为皮脂腺癌产生的皮脂痣。
A 53‐year‐old woman had had a pale‐brown lesion on her right cheek and neck from birth. Since she was about 40 years old, part of the lesion had gradually elevated and increased in size. At the first examination, there was a huge mass measuring 110 × 70 × 35 mm on the right cheek. A wide local excision of the area including a superficial parotidectomy and submandibular lymph node dissection was performed, followed by full thickness skin grafting. Histological examination of the tumor revealed an invasive dermal neoplasm characterized by lobes that were composed of foamy cells stained with Sudan‐IV mixed with many atypical cells showing remarkable variation in the shapes and sizes of their nuclei. The surrounding epithelial changes were consistent with nevus sebaceus. From these findings, the gigantic tumor was diagnosed as a sebaceous carcinoma arising in nevus sebaceus.