Lateral position decreases collapsibility of the passive pharynx in patients with obstructive sleep apnea
Lateral position decreases collapsibility of the passive pharynx in patients with obstructive sleep apnea
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DOI：
10.1097/00000542-200210000-00006
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发表时间：
2002-10-01
期刊：
影响因子：
8.8
通讯作者：
Nishino, T
中科院分区：
文献类型：
--
作者：
Isono, S;Tanaka, A;Nishino, T
背景：以前曾报道过阻塞性睡眠呼吸暂停患者侧卧位时夜间阻塞事件减少。然而，很少有资料是关于机制的改善和精确的咽部网站的影响，侧卧位。作者测试的假设，被动咽的结构特性的变化，通过改变身体的位置，从仰卧到lateral.Method总肌肉麻痹诱导全身麻醉8例阻塞性睡眠呼吸暂停综合征，消除神经肌肉因素有助于咽通畅。在不同的静态气道压力下，通过内窥镜测量咽的横截面积。结果：侧卧位的静态压力-面积曲线高于仰卧位，腭后气道和舌后气道的最大截面积增加，关闭压力降低。结论：侧卧位的静态压力-面积曲线与仰卧位的静态压力-面积曲线基本一致。侧卧位在结构上改善了阻塞性睡眠呼吸暂停患者被动咽气道的维持。
Background Reduction of nocturnal obstructive events during lateral position in patients with obstructive sleep apnea was previously reported. However, little information is available regarding mechanisms of the improvement and the precise pharyngeal site influenced by the lateral position. The authors tested the hypothesis that structural properties of the passive pharynx change by changing the body position from supine to lateral.Method Total muscle paralysis was induced with general anesthesia in eight patients with obstructive sleep apnea, eliminating neuromuscular factors contributing to pharyngeal patency. The cross-sectional area of the pharynx was measured endoscopically at different static airway pressures. Comparison of static pressure-area plot between the positions allowed assessment of the influence of the position change on the mechanical properties of the pharynx.Results: The static pressure-area curves of the lateral position were above those of the supine position, with increasing maximum cross-sectional area and decreasing the closing pressure at both retropalatal and retroglossal airways.Conclusions: Lateral position structurally improves maintenance of the passive pharyngeal airway in patients with obstructive sleep apnea.