Stimulant rebound: How common is it and what does it mean?
Stimulant rebound: How common is it and what does it mean?
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DOI：
10.1089/104454603322163853
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发表时间：
2003-06-01
影响因子：
1.9
通讯作者：
Kelly, KL
中科院分区：
文献类型：
--
作者：
Carlson, GA;Kelly, KL
目的：检查率和影响的兴奋剂引起的反弹的行为恶化，可能会发生的兴奋剂药物磨损off.Methods：本研究比较护士观察夜班相比，在149精神病住院儿童治疗短效兴奋剂，通常哌甲酯，比较非药物治疗和兴奋剂治疗states.Results：行为恶化（反弹），日班。在至少服用一剂兴奋剂的儿童中，30%的儿童出现了这种情况，但只有8.7%的儿童严重到足以停止治疗。经历反弹的儿童没有不同的临床从那些没有。结论：反弹的存在，发生显着的精神病住院儿童注意缺陷多动障碍的不到10%，并没有出现具有特定的诊断意义。
Objective: To examine rates and implications of stimulant-induced rebound-the behavioral deterioration that may occur as stimulant medications wear off.Methods: This study compares nurse observations on evening shifts compared to day shifts in 149 psychiatrically hospitalized children treated with short-acting stimulants, usually methylphenidate, comparing nonmedication and stimulant-treated states.Results: Behavioral deterioration (rebound),. was observed in 30% of children on at least one dose of stimulants but was serious enough to discontinue treatment in only 8.7%. Children experiencing rebound did not differ clinically from those who did not.Conclusions: Rebound exists, occurs significantly in less than 10% of psychiatrically hospitalized children with attention deficit hyperactivity disorder, and does not appear to have specific diagnostic significance.