Type-2 diabetes and carotid stenosis: a proposal for a screening strategy in asymptomatic patients

Type-2 diabetes and carotid stenosis: a proposal for a screening strategy in asymptomatic patients
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DOI:
10.1191/1358863x06vm677oa
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发表时间:
2006-01-01
期刊:
影响因子:
3.5
通讯作者:
Laskar, M.
Laskar, M.
中科院分区:
医学3区
文献类型:
--
作者:
Lacroix, P.;Aboyans, V.;Laskar, M.

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这项前瞻性观察性研究的目的是确定无症状糖尿病人群中颈动脉粥样硬化的患病率,并确定筛查优化的预测因素。总共300例2型糖尿病患者(男性166例,女性134例)接受了体格检查和颈动脉双工扫描。近期发生脑血管事件(= 60%或闭塞)的患者占4.7%;颈动脉粥样硬化患病率为68.3%。糖尿病视网膜病变(or: 3.62; 95% CI: 1.12-11.73)、踝肱指数(ABI) 60%狭窄在有冠心病或ABI病史的男性中发生率最高
The objective of this prospective observational study was to establish the prevalence of carotid atherosclerosis in an asymptomatic diabetic population and to determine predictive factors for a screening optimization. A total of 300 consecutive type-2 diabetic subjects (166 males, 134 females) underwent a physical examination and duplex carotid scanning. Patients with a recent cerebrovascular event (= 60% or occlusion was 4.7%; the prevalence of carotid atherosclerosis was 68.3%. Risk factors for stenosis >= 60% or occlusion were the presence of diabetic retinopathy (OR: 3.62; 95% CI: 1.12-11.73), ankle-brachial index (ABI) 60% stenosis is highest among men with a history of coronary heart disease or an ABI