Sperm-like nanocarriers for ultrafast delivery of antisense DNA
Sperm-like nanocarriers for ultrafast delivery of antisense DNA
复制标题
用于超快速递送反义 DNA 的类精子纳米载体
DOI：
10.1039/d2nr02050e
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发表时间：
2022
期刊：
影响因子：
6.7
通讯作者：
Xiaoli Zhu
中科院分区：
文献类型：
--
作者：
Xiaochen Tang;Tianshu Chen;Huinan Chen;Sinuo Yu;Siyu Cao;Chenbin Liu;Yonggeng Ma;Fenyong Sun;Qiuhui Pan;Xiaoli Zhu
纳米精子被开发用于将反义DNA超快递送到癌细胞中。作为“尾部”货物的反义DNA由“头部”的银纳米团簇携带，可以迅速转运到细胞中，从而抑制细胞增殖。
The nano-sperm is developed for ultrafast delivery of antisense DNA into cancer cells. Carried by silver nanoclusters at the “head”, antisense DNA as the cargo at the “tail” can be transported into cells rapidly, thereby inhibiting cell proliferation.