Acceleration of integra incorporation in complex tissue defects with subatmospheric pressure
Acceleration of integra incorporation in complex tissue defects with subatmospheric pressure
复制标题
DOI：
10.1097/01.prs.0000112746.67050.68
复制
发表时间：
2004-04-15
影响因子：
3.6
通讯作者：
Argenta, LC
中科院分区：
文献类型：
--
作者：
Molnar, JA;DeFranzo, AJ;Argenta, LC
为了加速血管形成并简化 Integra（新泽西州萨默维尔的 Ethicon, Inc.）的护理，对 8 名具有复杂伤口的患者（年龄范围为 2 至 60 岁）使用了局部负压。 62.5% 的病例暴露骨头，50% 暴露关节，37.5% 暴露肌腱，25% 暴露肠道。预计 Integra 的采用率为 96%。分层植皮手术时间4～11天，平均7.25天，成功率93%。使用该技术没有观察到不良副作用。与之前发表的结果相比，即使是复杂的伤口，负压的应用也提高了 Integra 的血管化率和时间。该技术可能是瓣关闭的实用替代方案。
In an effort to accelerate vascularization and simplify the care of Integra (Ethicon, Inc., Somerville, NJ.), topical subatmospheric pressure was used for eight patients (age range, 2 to 60 years) with complex wounds. Bone was exposed in 62.5 percent of cases, joint in 50 percent, tendon in 37.5 percent, and bowel in 25 percent. The estimated Integra take rate was 96 percent. Split-thickness skin grafting was performed at 4 to 11 days (mean, 7.25 days), with a 93 percent take rate. No adverse side effects were observed with this technique. Application of subatmospheric pressure improved the take rate and time to vascularization of Integra, compared with previous published results, even with complicated wounds. This technique may be a practical alternative to flap closure.