Novel Magnified Single-Balloon Enteroscopy Enables Observation of Jejunal White Spots Associated with Lymphangiectasia

Novel Magnified Single-Balloon Enteroscopy Enables Observation of Jejunal White Spots Associated with Lymphangiectasia
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新型放大单球囊肠镜检查能够观察与淋巴管扩张相关的空肠白斑

DOI:
10.1159/000493578
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发表时间:
2018
期刊:
影响因子:
2.3
通讯作者:
Terai Shuji
Terai Shuji
中科院分区:
医学3区
文献类型:
--
作者:
Tominaga Kentaro;Tsuchiya Atsunori;Kawata Yuzo;Yokoyama Junji;Terai Shuji

文献摘要

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一位59岁的女性被诊断为原发性肠淋巴管扩张症(PIL),胶囊肠镜检查和活检标本的组织病理学检查证实了她的特征性表现。我们使用新开发的单球囊放大肠镜(SIF-Y0007)观察异常的空肠黏膜。常规观察显示乳糜漏。然而,在这个新的范围内,我们可以看到分散的白色绒毛,代表从肿胀的空肠病变内扩张的粘膜下淋巴血管(D2-40阳性)突出的肠绒毛内扩张的淋巴管。本报告首次描述了使用新开发的放大肠镜清晰观察到的PIL患者的白色绒毛。技术的进步和病理数据的积累将进一步提高我们对这种疾病实体的病理生理方面的理解,甚至在空肠。
A 59-year-old woman was diagnosed with primary intestinal lymphangiectasia (PIL), with characteristic findings on capsule enteroscopy and confirmation by histopathological examination of biopsy specimens. We viewed the abnormal jejunal mucosa using a newly developed magnifying single-balloon enteroscope (SIF-Y0007). Conventional observation showed leakage of chyle. However, using this new scope, we could see scattered white villi, representing dilated lymphatic vessels within the intestinal villi protruding from the dilated submucosal lymphoid vessels (D2–40 positive) within an edematous jejunal lesion. This report is the first to describe the white villi in a patient with PIL observed clearly using a newly developed magnifying enteroscope. Technological advancements and the accumulation of reported pathological data would further improve our understanding of the pathophysiological aspects of this disease entity, even in the jejunum.