Mesoporous-Silica-Functionalized Nanoparticles for Drug Delivery
Mesoporous-Silica-Functionalized Nanoparticles for Drug Delivery
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DOI：
10.1002/chem.201500578
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发表时间：
2015-09-28
影响因子：
4.3
通讯作者：
Carcel, Carole
中科院分区：
文献类型：
--
作者：
Giret, Simon;Man, Michel Wong Chi;Carcel, Carole
The ever-growing interest for finding efficient and reliable methods for treatment of diseases has set a precedent for the design and synthesis of new functional hybrid materials, namely porous nanoparticles, for controlled drug delivery. Mesoporous silica nanoparticles (MSNPs) represent one of the most promising nanocarriers for drug delivery as they possess interesting chemical and physical properties, thermal and mechanical stabilities, and are biocompatibile. In particular, their easily functionalizable surface allows a large number of property modifications further improving their efficiency in this field. This Concept article deals with the advances on the novel methods of functionalizing MSNPs, inside or outside the pores, as well as within the walls, to produce efficient and smart drug carriers for therapy.
