Minimally invasive cardiac surgery in a patient with osteopetrosis and symptomatic mitral regurgitation
Minimally invasive cardiac surgery in a patient with osteopetrosis and symptomatic mitral regurgitation
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骨硬化症和症状性二尖瓣反流患者的微创心脏手术
DOI：
10.1111/jocs.15153
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发表时间：
2020
影响因子：
1.6
通讯作者：
E. Tayama
中科院分区：
文献类型：
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作者：
Takanori Kono;Kazuyoshi Takagi;E. Tayama
骨质疏松症是一种罕见的遗传性骨骼发育障碍，由破骨细胞功能障碍引起，骨密度增加。虽然很少有研究调查骨质疏松症患者的心血管疾病，但胸骨切开术在这种情况下的结果尚不清楚。我们报告的情况下，患者与骨质疏松和严重的二尖瓣反流。一例63岁女性劳力性呼吸困难，心尖处可听到反流性收缩期杂音。经胸超声心动图显示二尖瓣前外侧后小叶脱垂导致严重的二尖瓣返流。影像学检查显示骨密度增加（与骨质疏松一致）。考虑到胸骨正中切口的风险，我们通过右小开胸行微创心脏手术治疗二尖瓣反流。术前影像学显示肋骨硬化改变；然而，获得的足够的手术视图涉及肋间隙。无二尖瓣残余返流，术后病程良好。据我们所知，这是首例微创心脏手术治疗二尖瓣返流伴骨质疏松的病例报告。
Osteopetrosis is a rare hereditary bone development disorder caused by osteoclast dysfunction, which increases bone density. Although few studies have investigated cardiovascular disease in osteopetrosis, sternotomy outcomes in this condition are unclear. We report the case of a patient with osteopetrosis and severe mitral regurgitation. A 63‐year‐old woman with exertional dyspnea had regurgitant systolic murmur audible at the apex. Transthoracic echocardiography showed severe mitral regurgitation due to posterior leaflet prolapse on the anterolateral side. Radiological findings revealed increased bone density (consistent with osteopetrosis). Considering risks in median sternotomy, we performed minimally invasive cardiac surgery through right minithoracotomy for mitral regurgitation. Preoperative imaging showed sclerotic rib changes; nevertheless, sufficient surgical views obtained involved the intercostal space. No residual mitral regurgitation was observed, and the postoperative course was good. To the best of our knowledge, this is the first case report on minimally invasive cardiac surgery for mitral regurgitation with osteopetrosis.
双极髋关节置换术治疗成人常染色体显性骨石症 II 型股骨粗隆下骨不连：病例报告
DOI：
--
发表时间：
2011
期刊：
The Journal of Orthopaedic science 2011
影响因子：
--
作者：
Sonohata M;Olubo T;Ono H;Mawatari M;Hotokebuchi T
通讯作者：
Hotokebuchi T