FeCl3-catalyzed cascade cyclization in one pot: synthesis of ring-fused tetrahydroquinoline derivatives from arylamines and N-substituted lactams.

FeCl3-catalyzed cascade cyclization in one pot: synthesis of ring-fused tetrahydroquinoline derivatives from arylamines and N-substituted lactams.
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DOI:
10.1021/jo400979h
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发表时间:
2013-07
期刊:
The Journal of organic chemistry
影响因子:
--
通讯作者:
Manman Sun;Tianshui Zhang;W. Bao
Manman Sun;Tianshui Zhang;W. Bao
中科院分区:
其他
文献类型:
--
作者:
Manman Sun;Tianshui Zhang;W. Bao

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Multiple cross-dehydrogenative-coupling reactions catalyzed by FeCl3 in one pot were developed. Arylamines and N-substituted lactams were reacted, and ring-fused tetrahydroquinoline derivatives were formed by two C-C bonds and one C-N bond formation as well as one C-N bond cleavage. The lactams were also used as solvent.