HIV Disclosure to Family Members and Medication Adherence: Role of Social Support and Self-efficacy
HIV Disclosure to Family Members and Medication Adherence: Role of Social Support and Self-efficacy
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DOI：
10.1007/s10461-019-02456-1
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发表时间：
2020-01-01
影响因子：
4.4
通讯作者：
Zhou, Yuejiao
中科院分区：
文献类型：
--
作者：
Mi, Tianyue;Li, Xiaoming;Zhou, Yuejiao
尽管抗逆转录病毒疗法（ART）通过抑制病毒从而防止艾滋病毒继续传播并降低艾滋病相关的发病率和死亡率，对艾滋病毒感染者（PLWH）至关重要，但最佳ART坚持率仍然很低。披露艾滋病毒状况被认为是坚持抗逆转录病毒治疗的关键预测因素。然而，很少有研究探讨披露和药物依从性之间的关联的机制。本研究旨在探讨社会支持和自我效能感在艾滋病信息披露与抗逆转录病毒治疗依从性之间的中介作用。中国的PLWH提供了关于HIV披露、ART依从性、对药物依从性的感知社会支持、依从性自我效能和社会人口学信息的数据。通径分析显示，向家庭成员披露信息通过社会支持和自我效能感对依从性产生显著的间接影响。我们的研究结果表明，艾滋病毒的披露可能会积极影响ART坚持通过两个心理社会途径：社会支持和自我效能。未来的干预措施，以提高药物依从性PLWH应考虑针对这两个因素。
Although antiretroviral therapy (ART) is vital to people living with HIV (PLWH) by suppressing the virus and in turn preventing onward HIV transmission and reducing AIDS-related morbidity and mortality, the rates of optimal ART adherence continuously remain low. Disclosure of HIV status is considered to be a critical predictor of ART adherence. However, few studies have explored the mechanisms underlying the association between disclosure and medication adherence. The current study aims to examine the mediating role of social support and self-efficacy underlying the relationship between HIV disclosure to family members and ART adherence. PLWH in China provided data on HIV disclosure, ART adherence, perceived social support on medication adherence, adherence self-efficacy, and social-demographic information. The path analyses revealed that disclosure to family members had significant indirect effects on adherence via social support and self-efficacy. Our findings suggested that HIV disclosure might positively affect ART adherence through two psychosocial pathways: social support and self-efficacy. Future intervention to improve medication adherence among PLWH should consider targeting these two factors.