An ultrastructural examination of early ventral root formation in amphibia
An ultrastructural examination of early ventral root formation in amphibia
复制标题
两栖动物早期腹根形成的超微结构检查
DOI：
10.1002/cne.901990407
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发表时间：
1981
影响因子：
2.5
通讯作者：
M. Singer
中科院分区：
文献类型：
--
作者：
R. H. Nordlander;J. Singer;Ruth Beck;M. Singer
用电镜观察了两栖动物胚胎和尾再生过程中神经管与肌瘤早期相互作用的形态。观察到两种类型的接触。在肌瘤尚未分割的最原始水平，多个粘接剂型接触将神经管和肌瘤连接起来。在新近分节的区域，可以辨认出早期的腹侧根是一到五个轴突的小束，延伸到肌瘤的短距离。每个节段只有一个束，除了轴突外，每个束总是包含一个或多个原始胶质细胞过程，这些胶质细胞过程伴随着轴突离开脊髓。在根出口处，原始胶质突起向根内输送轴突。脊髓的细胞结构和新根表明，当运动轴突离开脊髓向目标延伸时，原始胶质细胞可能在寻路中发挥作用。
The morphology of early interactions between neural tube and myotome in the amphibian embryo and tail regenerate was examined using the electron microscope. Two types of contacts were observed. At the most primitive level where the myotome was yet unsegmented, multiple adhesive‐type contacts linked neural tube and myotome. In newly segmented areas early ventral roots were recognizable as small bundles of one to five axons extending the short distance to the myotome. There was only one bundle per segment and in addition to axons, each bundle always contained one or more primitive glial cell processes which accompanied axons as they left the cord. At points of root exit primitive glial processes appeared to funnel axons into the root. The cytoarchitecture of the cord and the new roots suggested that the primitive glia may play a role in pathfinding for motor axons as they leave the cord and extend toward their targets.