A standard test phantom for the performance assessment of magnetic resonance guided high intensity focused ultrasound (MRgHIFU) thermal therapy devices
A standard test phantom for the performance assessment of magnetic resonance guided high intensity focused ultrasound (MRgHIFU) thermal therapy devices
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DOI：
10.1080/02656736.2021.2017023
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发表时间：
2022-12-31
影响因子：
3.1
通讯作者：
Miloro, P.
中科院分区：
文献类型：
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作者：
Ambrogio, S.;Baesso, R. M.;Miloro, P.
目的：高强度聚焦超声(HIFU)的测试对象需要用于治疗的标准化和定义、质量保证(QA)、中心间结果的比较和设备的校准。这项研究描述了一种HIFU测试对象，它在与磁共振(MR)和超声波兼容的参考材料中提供随时间变化的温度测量。材料和方法：以T型细丝热电偶为传感器，对粘性发热伪影的5种校正方法进行了评价。该模型在MR-HIFU飞利浦Sonalleve设备上进行了为期12个月的测试，证明了评估该设备性能的稳定性和有效性。结果：这项研究提供了有关MR-HIFU会议的有用信息，并强调了现有质量保证和监测方法的潜在局限性。在三种MR平面图(冠状面、矢状面、横面面)上，MR温度计的读数不同，特别是当病灶靠近软组织/骨界面时，MR信号丢失，温度和热剂量被低估(三个平面图之间的差异为138%)，说明了沿整个声道进行温度监测的重要性。结论：该测试对象简单易用，可作为MR引导HIFU和潜在超声引导设备的培训、质量保证、研发的有效工具。
Purpose: Test objects for High Intensity Focused Ultrasound (HIFU) are required for the standardization and definition of treatment, Quality Assurance (QA), comparison of results between centers and calibration of devices. This study describes a HIFU test object which provides temperature measurement as a function of time, in a reference material compatible with Magnetic Resonance (MR) and ultrasound. Materials and methods: T-Type fine wire thermocouples were used as sensors and 5 correction methods for viscous heating artifacts were assessed. The phantom was tested in a MR-HIFU Philips Sonalleve device over a period of 12 months, demonstrating stability and validity to evaluate the performance of the device. Results: The study furnished useful information regarding the MR-HIFU sessions and highlighted potential limitations of the existing QA and monitoring methods. The importance of temperature monitoring along the whole acoustic path was demonstrated as MR Thermometry readings differed in the three MR plane views (coronal, sagittal, transverse), in particular when the focus was near a soft-tissue/bone interface, where there can be an MR signal loss with significant temperature and thermal dose underestimation (138% variation between the three plane views). Conclusions: The test object was easy to use and has potential as a valid tool for training, QA, research and development for MR guided HIFU and potentially ultrasound guided devices.