Feasible pickup from intact ossicular chain with floating piezoelectric microphone.
Feasible pickup from intact ossicular chain with floating piezoelectric microphone.
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DOI：
10.1186/1475-925x-11-10
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发表时间：
2012-02-22
影响因子：
3.9
通讯作者：
Gao Z
中科院分区：
文献类型：
--
作者：
Kang HY;Na G;Chi FL;Jin K;Pan TZ;Gao Z
为了满足全植入式人工耳蜗（TICI）的植入要求，已经开发了许多麦克风。然而，一个生物相容性的，而不破坏听骨链的完整性仍在调查中。这种可植入的浮置压电传声器（FPM）已被制造出来，并在我们实验室的体外测试中显示出有效的电声性能。我们检查了它是否从完整的听骨链敏感地拾取，并假设它是否是最佳的植入物。动物对照实验：选用成年猫5只（8耳）作为实验动物，测试FPM的电声性能。研究了三组：（1）实验组（锤骨上）：将FPM粘在完整听骨链的锤骨柄上;（2）阴性对照组（体内）：仅将FPM挂在鼓室内;（3）阳性对照组（Hy-M30）：将HiFi商用麦克风放置在实验耳附近。测试扬声器在0.25 ~ 8.0kHz范围内有序地播放纯音。耳内的FPM和HiFi麦克风同时拾取声音振动，并记录为.wav文件进行分析。FPM在2.0 kHz以上的频率范围内敏感地、平坦地转换声振动，而在1.0 kHz以下的过载质量下效率低下。虽然HiFi麦克风比FPM更有效，但在3.0 kHz和8.0 kHz下没有显著差异。只要应用微机电系统和压电陶瓷材料技术的改进，使其重量减轻、体积缩小，研制用于未来TICI和TIHA系统的植入式FPM是可行的。
Many microphones have been developed to meet with the implantable requirement of totally implantable cochlear implant (TICI). However, a biocompatible one without destroying the intactness of the ossicular chain still remains under investigation. Such an implantable floating piezoelectric microphone (FPM) has been manufactured and shows an efficient electroacoustic performance in vitro test at our lab. We examined whether it pick up sensitively from the intact ossicular chain and postulated whether it be an optimal implantable one. Animal controlled experiment: five adult cats (eight ears) were sacrificed as the model to test the electroacoustic performance of the FPM. Three groups were studied: (1) the experiment group (on malleus): the FPM glued onto the handle of the malleus of the intact ossicular chains; (2) negative control group (in vivo): the FPM only hung into the tympanic cavity; (3) positive control group (Hy-M30): a HiFi commercial microphone placed close to the site of the experiment ear. The testing speaker played pure tones orderly ranged from 0.25 to 8.0 kHz. The FPM inside the ear and the HiFi microphone simultaneously picked up acoustic vibration which recorded as .wav files to analyze. The FPM transformed acoustic vibration sensitively and flatly as did the in vitro test across the frequencies above 2.0 kHz, whereas inefficiently below 1.0 kHz for its overloading mass. Although the HiFi microphone presented more efficiently than the FPM did, there was no significant difference at 3.0 kHz and 8.0 kHz. It is feasible to develop such an implantable FPM for future TICIs and TIHAs system on condition that the improvement of Micro Electromechanical System and piezoelectric ceramic material technology would be applied to reduce its weight and minimize its size.