The epidemiology of abdominal aortic diameter
The epidemiology of abdominal aortic diameter
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DOI：
10.1016/j.jvs.2008.02.031
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发表时间：
2008-07-01
影响因子：
4.3
通讯作者：
Criqui, Michael H.
中科院分区：
文献类型：
--
作者：
Allison, Matthew A.;Kwan, Kevin;Criqui, Michael H.
背景。腹主动脉的直径对于腹主动脉瘤的诊断至关重要。本研究旨在确定三个不同位置的腹主动脉直径与传统心血管疾病危险因素以及钙化动脉粥样硬化之间的关联。方法。共有 504 名患者（41% 为女性）接受了电子束计算机断层扫描 (EBCT) 全身扫描以及心血管疾病危险因素的标准化评估。对所得 EBCT 图像进行回顾性询问，了解腹主动脉的直径，其正好位于肠系膜上动脉 (SMA) 下方、略高于主动脉分叉处以及 SMA 和分叉处之间的中点。结果。患者平均年龄为 57.8 岁。 SMA 处的平均 (SD) 直径为 21.3 (2.9) 毫米，中点处的平均 (SD) 直径为 19.3 (2.5) 圈，分叉处的平均 (SD) 直径为 18.6 (2.2) 圈。在包含传统心血管疾病危险因素的模型中，年龄（标准化 beta = 0.96）、男性（beta = 3.06）和体重指数（标准化 beta = 0.68）与 SMA 主动脉直径增加显着相关（所有 P < .01）。这些变量的关联显着性与中点和分叉处的主动脉直径相同。此外，腹主动脉和髂动脉钙评分每增加 1 个单位，SMA 处主动脉直径分别增加 0.13 毫米（P < .01）和 0.09 毫米（P = .02）。中点（分别为 beta = 0.19，P < .01；beta = 0.12，P = .01）和分叉（分别为 beta = 0.09，P < .04；beta = 0.09，P = .03）的结果相似。结论。年龄、性别、体重指数以及腹主动脉和髂动脉钙化动脉粥样硬化的存在和程度与主动脉直径增加显着相关，独立于其他心血管疾病危险因素。
Background. The diameter of the abdominal aorta is central to the diagnosis of abdominal aortic aneurysm. This study aimed to determine the associations between the diameter of the abdominal aorta at three distinct locations and the traditional cardiovascular disease risk factors as well as calcified atherosclerosis.Methods. A total of 504 patients (41% women) underwent whole body scanning by electron beam computed tomography (EBCT) and a standardized assessment for cardiovascular disease risk factors. The resulting EBCT images were retrospectively interrogated for the diameter of the abdominal aorta just inferior to the superior mesenteric artery (SMA), just superior to the aortic bifurcation, and at the midpoint between the SMA and bifurcation.Results. Mean patient age was 57.8 years. The mean (SD) diameter was 21.3 (2.9) mm at the SMA, 19.3 (2.5) turn at the midpoint, and 18.6 (2.2) turn at the bifurcation. In a model containing the traditional cardiovascular disease risk factors, age (standardized beta = 0.96), male sex (beta = 3.06), and body mass index (standardized beta = 0.68) were significantly associated with increasing aortic diameter at the SMA (P < .01 for all). The significance of the associations for these variables was the same for aortic diameter at the midpoint and bifurcation. Furthermore, a 1-unit increment in the calcium score in the abdominal aorta and iliac arteries was associated with 0.13-mm, (P < .01) and 0.09-mm, (P = .02) increases, respectively, in aortic diameter at the SMA. The results were similar for the midpoint (beta = 0.19, P < .01; beta = 0.12, P = .01, respectively) and bifurcation (beta = 0.09, P < .04; beta = 0.09, P = .03, respectively).Conclusions. Age, sex, body mass index, and the presence and extent of calcified atherosclerosis in both the abdominal aorta and iliac arteries are significantly associated with increasing aortic diameter independent of the other cardiovascular disease risk factors.