Immunologic dysfunction in Sickle cell anaemia.
Immunologic dysfunction in Sickle cell anaemia.
复制标题
镰状细胞性贫血的免疫功能障碍。
作者：
P. Hernández;C. Cruz;M. Santos;J. Ballester
Selected cellular immune parameters were studied in 20 patients with sickle cell anaemia (SCA). A moderate absolute lymphocytes was observed in SCA patients compared with the control group. There was no significant difference between patients and controls in the mean E-rosette percentage and absolute number. PHA transformation was decreased in 50% of SCA patients, and some of them showed cutaneous anergy. It was suggested that imparied cell-mediated immunity is another factor to be included among defective SCA host-defense mechanism.
