Bilateral primary breast cancer.

Bilateral primary breast cancer.
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双侧原发性乳腺癌。

DOI:
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发表时间:
1976
期刊:
Journal of the American Medical Association (JAMA)
影响因子:
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通讯作者:
Stephen J. Mcllveen
Stephen J. Mcllveen
中科院分区:
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文献类型:
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作者:
Howard J. Kesseler;W. Grier;I. Seidman;Stephen J. Mcllveen

文献摘要

被引文献

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自1962年至1972年,共收治乳腺癌967例。这些患者中有35人有第二原发肿瘤,其中50%是同时发现的。26%的双侧癌患者有癌症家族史。患者发现肿瘤的频率比内科医生更高,除非同时出现内科医生更成功的病例。病理检查显示,10%的肿瘤为粉刺样癌、小叶原位癌、乳头状癌或管状癌。异时性组双侧腋窝受累占50%。在同时发生的病例中,腋窝受累的频率较低。在某些高危患者中,乳房X光检查、第二乳房活组织检查和预防性乳房切除术应该会提高存活率。
Primary carcinoma of breast was treated in 967 patients from 1962 through 1972. Thirty-five of these patients had a second primary tumor of which 50% were discovered simultaneously. A family history for cancer was recorded in 26% of the patients with bilateral cancer. Patients found their tumor more often than the physician except in the simultaneous cases where the physician was more successful. Pathological examination showed 10% of the tumors were comedo, lobular carcinoma in situ, papillary, or tubular cancers. In the metachronous group, 50% of the axillae were involved on both sides. In the simultaneous cases the axilla was less frequently involved. Mammography, biopsies of the second breast, and prophylactic mastectomy in certain high-risk patients should improve survival rates.