Highly Efficient Cu(I)-Catalyzed Synthesis of N-Heterocycles through a Cyclization-Triggered Addition of Alkynes
Highly Efficient Cu(I)-Catalyzed Synthesis of N-Heterocycles through a Cyclization-Triggered Addition of Alkynes
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DOI：
10.1021/ja908883n
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发表时间：
2010-01-27
影响因子：
15
通讯作者：
Hammond, Gerald B.
中科院分区：
文献类型：
--
作者：
Han, Junbin;Xu, Bo;Hammond, Gerald B.
氨基炔（末端或内部）和末端炔通过 Cu(I) 催化的一锅串联加氢胺化/炔基化工艺以优异的产率提供官能化的五元、六元和七元 N-杂环。
An aminoalkyne (terminal or internal) and a terminal alkyne furnish functionalized five-, six-, and seven- membered N-heterocycles in excellent yields via a Cu(I)-catalyzed, one-pot, tandem hydroamination/alkynylation process.