Racial/ethnic and neighbourhood social vulnerability disparities in COVID-19 testing positivity, hospitalization, and in-hospital mortality in a large hospital system in Pennsylvania: A prospective study of electronic health records.

Racial/ethnic and neighbourhood social vulnerability disparities in COVID-19 testing positivity, hospitalization, and in-hospital mortality in a large hospital system in Pennsylvania: A prospective study of electronic health records.
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DOI:
10.1016/j.lana.2022.100220
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发表时间:
2022-06
期刊:
Lancet regional health. Americas
影响因子:
--
通讯作者:
Momplaisir F
Momplaisir F
中科院分区:
其他
文献类型:
--
作者:
Bilal U;Jemmott JB;Schnake-Mahl A;Murphy K;Momplaisir F

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使用监测数据记录了不同种族/民族或社区的COVID-19死亡率差异。我们的目的是描述种族/民族和社区社会脆弱性在COVID-19阳性率、住院率和死亡率方面的差异。我们从宾夕法尼亚大学卫生系统(UPHS)的COVID-19检测呈阳性或于2020年3月1日至2021年3月31日期间在五家UPHS医院因确诊COVID-19感染住院的所有个人的电子健康记录中获得数据。主要预测因素是种族/族裔和社区一级的社会脆弱性。主要结局为COVID-19检测阳性、因COVID-19住院以及因COVID-19住院后30天的住院死亡率。共有225,129名独立个体接受了COVID-19检测,18,995人的检测结果呈阳性。共有5,794名独特患者因COVID-19住院,511人在30天内死于医院。种族/族裔少数群体和社会脆弱性较高的社区居民有较高的检测阳性率和住院风险。我们在第一波中没有看到住院死亡率的差异,但在随后的几波中,西班牙裔和亚洲人的死亡率比白人高75%和68%。我们观察到,在COVID-19结果方面存在显著的种族/民族和邻里差异,特别是检测阳性率和住院几率,这突显了公平改善预防措施的重要性,以减少SARS-CoV-2感染,包括减少病毒暴露和确保疫苗接种的公平性。国立卫生研究院。
Disparities in COVID-19 mortality by race/ethnicity or neighborhood have been documented using surveillance data. We aimed to describe disparities by race/ethnicity and neighbourhood social vulnerability in COVID-19 positivity, hospitalization, and mortality. We obtained data from the electronic health records of all individuals who tested positive for COVID-19 in the University of Pennsylvania Health System (UPHS) or were hospitalized with confirmed COVID-19 infection in five UPHS hospitals from March 1, 2020, to March 31, 2021. The main predictors were race/ethnicity and neighbourhood-level social vulnerability. The main outcomes were COVID-19 test positivity, hospitalization with COVID-19, and 30-day in-hospital mortality following hospitalization with COVID-19. A total of 225,129 unique individuals received COVID-19 testing and 18,995 had a positive test result. A total of 5,794 unique patients were hospitalized with COVID-19 and 511 died in-hospital within 30 days. Racial/ethnic minority groups and residents of higher social vulnerability neighbourhoods had higher test positivity and risk of hospitalization. We did not see in-hospital mortality disparities during the first wave but observed 75% and 68% higher odds of death among Hispanic and Asians compared to Whites during subsequent waves. We observed significant racial/ethnic and neighbourhood disparities in COVID-19 outcomes, especially test positivity and odds of hospitalization, highlighting the importance of equitably improving access to preventive measures to reduce SARS-CoV-2 infection, including reducing exposure to the virus and ensuring equity in vaccination. National Institutes of Health.
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