Psychosocial outcome of TBI in children with unilateral frontal lesions
Psychosocial outcome of TBI in children with unilateral frontal lesions
复制标题
DOI：
10.1017/s1355617704102129
复制
发表时间：
2004-05-01
影响因子：
2.6
通讯作者：
Hunter, JV
中科院分区：
文献类型：
--
作者：
Levin, HS;Zhang, LF;Hunter, JV
为了评估单侧额叶损伤对儿童创伤性脑损伤（TBI）的心理社会和整体结局的影响，研究1比较了22名学龄儿童的匹配组，这些儿童患有或不患有单侧额叶损伤。研究2评估了18例TBI患者单侧额外病变的影响，并与18例非病变TBI患者进行了比较。采用交流、日常生活和社会化领域以及Vineland适应行为量表（VABS）中的适应不良行为量表评估心理社会结局，并采用格拉斯哥结局量表（GOS）测量总体结局。所有患者在受伤后至少3个月接受磁共振成像。额叶损伤的儿童在日常生活和社会化领域的得分更差，适应不良行为的频率更高，但在认知功能方面没有差异。额叶损伤组的残疾率是无额叶损伤组的两倍。额叶损伤的大小与社会化领域有关。病变侧没有影响，也没有存在额外病变（研究2）。单侧额叶损伤对儿童TBI的晚期心理社会结局有不利影响。
To evaluate effects of unilateral frontal lesions on psychosocial and global outcome of traumatic brain injury (TBI) in children, Study 1 compared matched groups of 22 school aged children who had sustained TBI either with or without unilateral frontal lesions. Study 2 evaluated effects of unilateral extrafrontal lesions in 18 TBI patients as compared with 18 nonlesional TBI patients. Communication, Daily Living, and Socialization domains and the Maladaptive Behavior Scale of the Vineland Adaptive Behavior Scales (VABS) were used to assess psychosocial outcome, and the Glasgow Outcome Scale (GOS) measured global outcome. All patients underwent magnetic resonance imaging at least 3 months post injury. Children with frontal lesions had worse scores on the Daily Living and Socialization domains and a higher frequency of maladaptive behavior than those without frontal lesions, but there was no difference in cognitive function. Disability was twice as common in the frontal lesion group relative to children without frontal lesions. Volume of frontal lesion was related to the Socialization domain. Side of lesion had no effect, nor did presence of an extrafrontal lesion (Study 2). Unilateral frontal lesions adversely affect late psychosocial outcome of TBI in children.