Jumbo forceps are superior to standard large-capacity forceps in obtaining diagnostically adequate inflammatory bowel disease surveillance biopsy specimens
Jumbo forceps are superior to standard large-capacity forceps in obtaining diagnostically adequate inflammatory bowel disease surveillance biopsy specimens
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DOI：
10.1016/j.gie.2007.11.023
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发表时间：
2008-08-01
影响因子：
7.7
通讯作者：
Elta, Grace H.
中科院分区：
文献类型：
--
作者：
Elmunzer, B. Joseph;Higgins, Peter D. R.;Elta, Grace H.
背景资料：在炎症性肠病（IBD）监测结肠镜检查中，活检标本数量的增加与更高的异型增生检出率相关。较大的活检标本也可能增加诊断yield.Objective：比较一个新的巨型钳与标准的大容量钳ill获得诊断充分IBD监测biopsy samples.Design：前瞻性单中心研究。作为标准IBD监测的一部分，使用巨型钳和标准大容量钳从直肠乙状结肠获得8对活检标本。结果测量：如果活检标本满足以下所有3个标准，则认为它们是足够的：（1）长度>= 3（2）渗透到粘膜肌层中，以及（3）< 20%挤压伪影。使用巨型钳获得足够活检标本的比例显著高于使用大容量对照钳获得的比例（67% vs 48%，P
Background: in inflammatory bowel disease (IBD) surveillance colonoscopy an increased number of biopsy specimens correlates with a higher dysplasia detection rate. Larger biopsy specimens may also increase the diagnostic yield.Objective: To compare a new jumbo forceps with a standard large capacity forceps ill obtaining diagnostically adequate IBD surveillance biopsy specimens.Design: Prospective single-center study.Patients and Methods: Twenty-four patients who were undergoing an IBD surveillance colonoscopy were enrolled. As part of standard IBD surveillance, 8 paired biopsy specimens were obtained from the rectosigmoid by using the jumbo forceps and a standard large-capacity forceps.Outcome Measurements: Biopsy specimens were deemed adequate if they met all 3 of the following criteria: (1) length >= 3 (2) penetration into the muscularis mucosa, and (3) < 20% crush artifact.Results: The proportion of adequate biopsy specimens obtained with the jumbo forceps was significantly higher than than it obtained with the large-capacity control forceps (67% vs 48%, P