CHRONIC CONDITIONS THAT LEAD TO FUNCTIONAL LIMITATION IN THE ELDERLY
CHRONIC CONDITIONS THAT LEAD TO FUNCTIONAL LIMITATION IN THE ELDERLY
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DOI：
10.1093/geronj/49.1.m28
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发表时间：
1994-01-01
期刊：
影响因子：
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通讯作者：
MCCAFFREY, D
中科院分区：
文献类型：
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作者：
BOULT, C;KANE, RL;MCCAFFREY, D
背景慢性疾病在老年人丧失功能性能力方面的作用直观上很重要，但没有得到很好的界定。该分析旨在确定导致严重功能限制发展的慢性疾病。1984年，对所有70岁或70岁以上的非住院美国平民进行了多阶段概率样本（n = 6，862）的功能完整的成员进行了采访。根据国家死亡指数的数据和1988年对幸存者的随访电话采访，受试者被分类为功能完整、功能受限（不能进行七项基本活动中的一项或多项）或死亡。在调整了运动习惯和人口统计学、社会经济学和心理社会因素的影响后，我们发现功能受限发展的最佳预测因子是脑血管疾病（OR = 2.14; 95%CL = 1. 15）。16，3.98）和关节炎（OR = 1.51; 95% CL = 1.08，2.11）。冠状动脉病变的危险性也接近统计学意义（OR = 1.49; 95%CL = 0.99，2.27）。将来，对脑血管疾病、关节炎和可能的冠状动脉疾病的一级预防或有效治疗可能会适度降低严重功能受限的发生率。
Background. The role of chronic medical conditions in elderly persons' loss of functional abilities is intuitively important but not well defined. This analysis was designed to identify chronic medical conditions that lead to the development of severe functional limitation.Methods. Functionally intact members of a multistage probability sample (n = 6,862) of all noninstitutionalized U.S. civilians age 70 years or older were interviewed in 1984. Based on data from the National Death Index and from follow-up telephone interviews in 1988 with survivors, subjects were classified as functionally intact, functionally limited (unable to perform one or more of seven essential activities), or deceased.Results. After adjusting for the effects of exercise habits and demographic, socioeconomic, and psychosocial factors, we found that the best predictors of the development of functional limitation were cerebrovascular disease (OR = 2.14; 95% CL = 1. 16, 3.98) and arthritis (OR = 1.51; 95% CL = 1.08, 2.11). The contribution of coronary artery disease also approached statistical significance (OR = 1.49; 95% CL = 0.99, 2.27).Conclusion. In the future, the primary prevention or effective treatment of cerebrovascular disease, arthritis, and possibly coronary artery disease may produce a modest reduction in the incidence of severe functional limitation.