Prevalence of Carotid Web in Patients with Acute Intracranial Stroke Due to Intracranial Large Vessel Occlusion

Prevalence of Carotid Web in Patients with Acute Intracranial Stroke Due to Intracranial Large Vessel Occlusion
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DOI:
10.1148/radiol.2017170094
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发表时间:
2018-03-01
期刊:
影响因子:
19.7
通讯作者:
Emmer, Bart J.
Emmer, Bart J.
中科院分区:
医学1区
文献类型:
--
作者:
Compagne, Kars C. J.;van Es, Ad C. G. M.;Emmer, Bart J.

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目的:调查颅内大血管闭塞所致急性缺血性卒中患者中症状性颈动脉网的患病率,确定颈动脉网患者的临床和影像学特征及其与缺血性卒中的相关性,并确定观察者间对颈动脉网评估的一致性。材料和方法:纳入了荷兰急性缺血性卒中血管内治疗多中心随机临床试验(MR CLEAN)中所有可评估颈动脉分叉的患者(n = 500)(n = 443)。通过计算机断层扫描(CT)血管造影术评价颈动脉分叉处颈动脉网的存在。通过描述性统计量列出颈动脉网明确患者的人口统计学、临床特征和影像学基线特征。观察者之间的协议检测颈动脉网进行了检查,通过使用kappa statistics.Results:11(2.5%)的颈动脉网被发现在有症状的一侧和两个(0.5%)的颈动脉网被发现在无症状侧。10例(91%)有症状的颈动脉网患者为女性。9例有症状的颈动脉网患者没有缺血性卒中的主要危险因素或其他原因(82%)。公平良好的观察者之间的协议(Kappa,0.72)观察诊断颈动脉网在CT angiography.Conclusion:颈动脉网在症状性颈动脉分叉处观察到2.5%的急性缺血性中风患者由于大血管闭塞,大多数诊断女性患者具有公平良好的观察者之间的协议。(C)RSNA,2017
Purpose: To investigate the prevalence of symptomatic carotid web in patients with acute ischemic stroke due to intracranial large vessel occlusion, to determine the clinical and imaging profile of patients with carotid web as well as their association with ischemic stroke, and to determine the interobserver agreement in the assessment of carotid webs.Materials and Methods: All patients (n = 500) of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN) in whom the carotid bifurcation could be assessed (n = 443) were included. The presence of a carotid web at the carotid bifurcations was evaluated at computed tomographic (CT) angiography. Demographics, clinical characteristics, and imaging baseline characteristics were presented by descriptive statistics for patients with an identified carotid web. Interobserver agreement in the detection of carotid webs was examined by using kappa statistics.Results: Eleven (2.5%) carotid webs were found at the symptomatic side and two (0.5%) carotid webs were found at the asymptomatic side. Ten (91%) patients with a symptomatic carotid web were female. Nine patients with a symptomatic carotid web did not have major risk factors or other causes for ischemic stroke (82%). Fair to good interobserver agreement (kappa, 0.72) was observed for diagnosing carotid webs at CT angiography.Conclusion: Carotid webs at the symptomatic carotid bifurcation were observed in 2.5% of the patients with acute ischemic stroke due to large vessel occlusion and were mostly diagnosed in female patients with a fair to good interobserver agreement. (C) RSNA, 2017