Pain and Risk Behaviors Among HIV-Infected Persons in St. Petersburg, Russia.
Pain and Risk Behaviors Among HIV-Infected Persons in St. Petersburg, Russia.
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俄罗斯圣彼得堡艾滋病毒感染者的疼痛和危险行为。
DOI：
10.1007/s10461-016-1593-5
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发表时间：
2017
影响因子：
4.4
通讯作者：
Samet,JeffreyH
中科院分区：
文献类型：
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作者：
Tsui,JudithI;Cheng,DebbieM;Coleman,SharonM;Blokhina,Elena;Gnatienko,Natalia;Bryant,Kendall;Krupitsky,Evgeny;Zvartau,Edwin;Samet,JeffreyH
我们分析了来自俄罗斯彼得堡的HIV感染ART初治患者观察队列的基线数据，以探讨疼痛是否与HIV风险行为相关。主要结局是（1）过去90天内无保护的阴道或肛交;（2）过去一个月内共用针头或设备。次要结局包括：性行为前饮酒、当前注射毒品使用、无保护性行为和共享事件的次数以及过去一个月注射的天数。主要自变量是过去一周的疼痛。多变量回归模型适用于结局。调整后，与无保护性行为的关联具有临界显著性（AOR = 2.06; 95% CI 0.98-4.36，p = 0.058）;过去一周的任何疼痛与共用针头/设备之间没有显著关联（AOR = 1.52; 95% CI 0.65-3.59，p = 0.33）。疼痛的参与者在性行为前报告饮酒的几率更高（AOR = 2.42; 95%CI 1.10-5.28，p = 0.03）。
We analyzed baseline data from an observational cohort of HIV-infected ART-naïve patients in St. Petersburg, Russia to explore whether pain was associated with HIV risk behaviors. The primary outcomes were (1) unprotected vaginal or anal sex in the past 90 days and (2) sharing of needles or equipment in the past month. Secondary outcomes included: use of alcohol prior to sex, current injection drug use, number of unprotected sex and sharing episodes, and days injected in the past month. The main independent variable was any past week pain. Multivariable regression models were fit for outcomes. After adjustment, the association with unprotected sex was of borderline significance (AOR = 2.06; 95 % CI 0.98–4.36, p = 0.058); there was no significant association between any past week pain and sharing of needles/equipment (AOR = 1.52; 95 % CI 0.65–3.59, p = 0.33). Participants with pain had higher odds of reporting alcohol use prior to sex (AOR = 2.42; 95 % CI 1.10–5.28, p = 0.03).