Gastroschisis prevalence substantially decreased from 2009 through 2018 after a 3-fold increase from 1997 to 2008
Gastroschisis prevalence substantially decreased from 2009 through 2018 after a 3-fold increase from 1997 to 2008
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DOI：
10.1016/j.jpedsurg.2020.03.010
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发表时间：
2020-12-01
影响因子：
2.4
通讯作者：
Tolia, Veeral N.
中科院分区：
文献类型：
--
作者：
Clark, Reese H.;Sousa, John;Tolia, Veeral N.
背景/目的：1998年至2013年，美国胃裂的发病率增加了300%。我们试图从一个大型NICU数据集中评估1997年至2018年美国胃裂患病率的趋势。方法：我们对1997年至2018年儿科临床数据仓库中的所有婴儿进行回顾性分析。患病率计算为胃裂的婴儿数量（在所有新生儿重症监护病房入院的婴儿中）除以新生儿重症监护病房婴儿总数。趋势是按年和按产妇年龄分层后进行分析的。结果：我们纳入了1433027名在研究期间出院的婴儿。1997年至2008年间，胃裂的患病率从每1000名婴儿2.9例上升到6.4例（p < 0.01），到2018年下降到每1000名婴儿3.3例（p < 0.01）。年轻妈妈(
Background/Purpose: Gastroschisis incidence increased 300% in the United States from 1998 to 2013. We sought to assess trends in gastroschisis prevalence in the United States from 1997 to 2018 from a large NICU dataset.Methods: We performed a retrospective review of all infants in the Pediatrix Clinical Data Warehouse from 1997 to 2018. Prevalence was calculated as number of infants with gastroschisis (among all NICU admissions) divided by the total number of NICU infants. Trends were analyzed by year and also after stratification of the cohort by maternal age.Results: We included 1,433,027 infants discharged over the study period. Between 1997 and 2008, the prevalence of gastroschisis increased from 2.9 to 6.4 per 1000 infants (p < 0.01) and then decreased to 3.3 per 1000 infants (p < 0.01) by 2018. Younger mothers (