Digital recording and analysis of esophageal pressure for patients with obstructive sleep apnea-hypopnea syndrome.
Digital recording and analysis of esophageal pressure for patients with obstructive sleep apnea-hypopnea syndrome.
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DOI：
10.1007/s11325-005-0015-0
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发表时间：
2005-06-01
期刊：
影响因子：
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通讯作者：
Kobayashi, Toshimitsu
中科院分区：
文献类型：
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作者：
Suzuki, Masaaki;Ogawa, Hiromasa;Kobayashi, Toshimitsu
为了评估阻塞性睡眠呼吸暂停低通气综合征 (OSAHS) 患者与睡眠相关的阻塞性呼吸事件，我们开发了一种食管压力 (Pes) 数字记录和分析技术，并阐明了 Pes 参数。使用微尖型压力传感器过夜记录 74 名 OSAHS 患者的 Pes。同时，记录所有患者的数字多导睡眠图。呼吸暂停末期 Pes 波动的平均最低点 (Pes Nadir) 范围为 -20.2 至 -147.4 cmH(2)O，平均值为 -53.6+/-2.9 cmH(2)O。平均 Pes Nadir 的相关性表明与最大 Pes 摆动与呼吸暂停持续时间的平均比率 (r(2)=0.70) 和 Pes 平均面积 (Pes Area) (r(2)=0.82) 呈线性关系。平均 Pes Nadir 和呼吸暂停低通气指数（AHI，范围为每小时 7.9 至 109.5；r(2)=0.66）、最低 SpO(2) (r(2)=0.60)、氧饱和度指数 (ODI) 大于 3 (r(2)=0.65)、觉醒指数 (r(2)=0.54) 和呼吸暂停指数之间存在显着相关性。平均 Pes 面积和 AHI 之间 (r(2)=0.63)、最小经皮动脉血氧饱和度 (SpO(2)；r(2)=0.57)、ODI (r(2)=0.69) 和唤醒指数 (r(2)=0.41)。研究发现，Pes 参数对于评估 OSAHS 患者睡眠相关阻塞性呼吸事件期间呼吸努力的严重程度具有重要意义。
To evaluate sleep-related obstructive breathing events in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), we developed a technique for digital recording and analysis of esophageal pressure (Pes) and elucidated the Pes parameters. Pes was recorded overnight with a microtip-type pressure transducer in 74 patients with OSAHS. Simultaneously, in all patients digital polysomnography was recorded. The mean nadir end-apneic Pes swing (Pes Nadir) ranged from -20.2 to -147.4 cmH(2)O, with a mean of -53.6+/-2.9 cmH(2)O. Correlation of the mean Pes Nadir indicated a linear relationship with the mean ratio of maximal Pes swing to apnea duration (r(2)=0.70) and the mean area of the Pes (Pes Area) (r(2)=0.82). Significant correlations were noted between the mean Pes Nadir and apnea-hypopnea index (AHI, ranging from 7.9 to 109.5 per hour; r(2)=0.66), minimum SpO(2) (r(2)=0.60), oxygen desaturation index (ODI) of more than 3 (r(2)=0.65), arousal index (r(2)=0.54), and between the mean Pes Area and AHI (r(2)=0.63), minimum percutaneous arterial oxygen saturation (SpO(2); r(2)=0.57), ODI (r(2)=0.69), and arousal index (r(2)=0.41). Pes parameters were found to be significant in the evaluation of the severity of the respiratory effort during the sleep-related obstructive breathing events for patients with OSAHS.