Total folate and folic acid intake from foods and dietary supplements in the United States: 2003-2006
Total folate and folic acid intake from foods and dietary supplements in the United States: 2003-2006
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DOI：
10.3945/ajcn.2009.28427
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发表时间：
2010-01-01
影响因子：
7.1
通讯作者：
Picciano, Mary Frances
中科院分区：
文献类型：
--
作者：
Bailey, Regan L.;Dodd, Kevin W.;Picciano, Mary Frances
背景资料：术语总叶酸摄入量用于表示食物中天然存在的叶酸以及来自强化食品和膳食补充剂的叶酸。叶酸被认为是一把双刃剑，因为它在预防神经管缺陷方面具有有益作用，但对某些癌症和认知功能可能有有害影响。以前的监测工作没有包括膳食补充剂中的叶酸，因此是不完整的。目的：我们的目标是联合收割机数据的膳食叶酸（通过两次24小时召回测量）和膳食补充剂中的叶酸（收集了30天的频率问卷）与使用偏差校正的最佳功率方法，以调整人内变异。设计：国家健康和营养检查调查（NHANES）是一项具有全国代表性的横断面调查。构建线性对比，以确定不同的饮食和总叶酸摄入量的年龄和种族，种族群体的性别;患病率不足和过量摄入presented.Results：在2003-2006年，53%的美国人口使用膳食补充剂; 34.5%使用膳食补充剂，含有叶酸。总叶酸摄入量（膳食叶酸当量）男性（813 +/- 14）高于女性（724 +/- 16），非西班牙裔白人（827 +/- 19）高于墨西哥裔美国人（615 +/- 11）和非西班牙裔黑人（597 +/- 12）; 29%的非西班牙裔黑人女性摄入不足。总叶酸和叶酸摄入量是最高的那些年龄> 50 y，和5%超过了可耐受的上限Intake Level.Conclusions：改善总叶酸摄入量是必要的目标亚组，其中包括育龄妇女和非西班牙裔黑人妇女，而其他人群的风险摄入过量。美国临床营养杂志2010;91：231-7.
Background: The term total folate intake is used to represent folate that occurs naturally in food as well as folic acid from fortified foods and dietary supplements. Folic acid has been referred to as a double-edged sword because of its beneficial role in the prevention of neural tube defects and yet possible deleterious effects on certain cancers and cognitive function. Previous monitoring efforts did not include folic acid from dietary supplements and are therefore not complete.Objective: Our objective was to combine data on dietary folate (as measured by two 24-h recalls) and folic acid from dietary supplements (collected with a 30-d frequency questionnaire) with the use of the bias-corrected best power method to adjust for within-person variability.Design: The National Health and Nutrition Examination Survey (NHANES) is a nationally representative, cross-sectional survey. Linear contrasts were constructed to determine differences in dietary and total folate intake for age and racial-ethnic groups by sex; prevalence of inadequate and excessive intakes is presented.Results: In 2003-2006, 53% of the US population used dietary supplements; 34.5% used dietary supplements that contained folic acid. Total folate intake (in dietary folate equivalents) was higher for men (813 +/- 14) than for women (724 +/- 16) and higher for non-Hispanic whites (827 +/- 19) than for Mexican Americans (615 +/- 11) and non-Hispanic blacks (597 +/- 12); 29% of non-Hispanic black women had inadequate intakes. Total folate and folic acid intakes are highest for those aged > 50 y, and 5% exceed the Tolerable Upper Intake Level.Conclusions: Improved total folate intake is warranted in targeted subgroups, which include women of childbearing age and non-Hispanic black women, whereas other population groups are at risk of excessive intake. Am J Clin Nutr 2010;91:231-7.