Blood pressure response to dietary sodium restriction in normotensive adults.
Blood pressure response to dietary sodium restriction in normotensive adults.
复制标题
血压正常的成年人对饮食钠限制的血压反应。
DOI：
10.1161/01.hyp.5.5.790
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Lang,CL
中科院分区：
文献类型：
--
作者：
Miller,JZ;Daugherty,SA;Weinberger,MH;Grim,CE;Christian,JC;Lang,CL
16对健康、血压正常的夫妻参加了一项研究，以调查减少饮食中钠摄入量（目标低于或等于60 mEq/天）对血压的影响。钠排泄量从对照组平均152.7 +/- 10.1 (SE) mEq/d降至69.5 +/- 4.5 mEq/d （p < 0.001）。结果显示，在一段时间的限钠后，收缩压（p < 0.001）和舒张压（p < 0.001）均显著降低。在整个组中，钾排泄量（58.4 +/- 3.2 vs 54.6 +/- 3.5 mEq/天）或体重（76.0 +/- 2.8 vs 75.3 +/- 2.7 kg）没有显著变化。尽管血压反应存在变异性，但血压的降低与限钠程度显著相关（r = 0.36, p < 0.03）。这些结果表明，血压对钠限制的反应可能不仅限于高血压患者，而且在血压正常的受试者中，这种反应是不均匀的。
Sixteen healthy, normotensive husband-wife pairs participated in a study to investigate the effect of reduction of dietary sodium intake (goal less than or equal to 60 mEq/day) on blood pressure. Sodium excretion decreased from a control average of 152.7 +/- 10.1 (SE) mEq/day to 69.5 +/- 4.5 mEq/day (p less than 0.001). Results indicated significant decreases in both systolic (p less than 0.001) and diastolic (p less than 0.001) blood pressure after a period of sodium restriction. In the entire group, there was no significant change in potassium excretion (58.4 +/- 3.2 vs 54.6 +/- 3.5 mEq/day) or body weight (76.0 +/- 2.8 vs 75.3 +/- 2.7 kg). Although there was variability in the blood pressure response, the decrease in blood pressure was significantly correlated with the magnitude of sodium restriction (r = 0.36, p less than 0.03). These results indicate that the blood pressure response to sodium restriction may not be limited to individuals with hypertension and that the response is heterogeneous in normotensive subjects.