Development and Assessment of a Computerized Index of Clinical Disease Activity in Systemic Lupus Erythematosus
Development and Assessment of a Computerized Index of Clinical Disease Activity in Systemic Lupus Erythematosus
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系统性红斑狼疮临床疾病活动计算机化指数的开发和评估
DOI：
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发表时间：
1988
期刊：
影响因子：
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通讯作者：
A. Zoma
中科院分区：
文献类型：
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作者：
D. Symmons;J. Coppock;P. Bacon;B. Bresnihan;D. Isenberg;P. Maddison;N. McHugh;M. Snaith;A. Zoma
英国和爱尔兰共和国的五个中心合作，根据医生治疗意图的原则，制作了一个系统性红斑狼疮临床疾病活动的计算机化指数。该指数分别评估了八个器官系统。尽管有一个全面的数据库，该指数已被证明是快速和易于使用的，并与其他两个疾病活动指数相比毫不逊色。它在系统性红斑狼疮疾病结局和新疗法的多中心研究中具有很大的潜力。
Five centres in Great Britain and the Republic of Ireland nave collaborated to produce a computerized index of clinical disease activity in systemic lupus erythematosus, based on the principle of the physician's intention to treat. The index assesses separately eight organ-based systems. The index has proved quick and easy to use despite a comprehensive database and compares favourably with two other indices of disease activity. It has great potential for use in multicentre studies of disease outcome and new therapies in systemic lupus erythematosus.