Focusing Attention on the Health Aspects of Foods Changes Value Signals in vmPFC and Improves Dietary Choice
Focusing Attention on the Health Aspects of Foods Changes Value Signals in vmPFC and Improves Dietary Choice
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DOI：
10.1523/jneurosci.6383-10.2011
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发表时间：
2011-07-27
影响因子：
5.3
通讯作者：
Rangel, Antonio
中科院分区：
文献类型：
--
作者：
Hare, Todd A.;Malmaud, Jonathan;Rangel, Antonio
注意力被认为在选择时刺激值的计算中起着关键作用，这表明注意力操纵可用于改善自控失误普遍存在的领域的决策。我们使用fMRI食物选择任务与非节食人类受试者调查是否外源性线索，直接注意食物的健康可以改善饮食选择。行为上，我们发现，受试者在健康提示的存在下做出了更健康的选择。与此同时，腹内侧前额叶皮层的刺激值信号对健康线索存在下的食物健康性的反应更敏感，并且这种效应受到背外侧前额叶皮层区域活动的调制。这些发现表明，成功的自我控制中使用的神经机制可以被外源性注意力线索激活，并提供了行为疗法和公共政策可以促进自我控制的过程的见解。
Attention is thought to play a key role in the computation of stimulus values at the time of choice, which suggests that attention manipulations could be used to improve decision-making in domains where self-control lapses are pervasive. We used an fMRI food choice task with non-dieting human subjects to investigate whether exogenous cues that direct attention to the healthiness of foods could improve dietary choices. Behaviorally, we found that subjects made healthier choices in the presence of health cues. In parallel, stimulus value signals in ventromedial prefrontal cortex were more responsive to the healthiness of foods in the presence of health cues, and this effect was modulated by activity in regions of dorsolateral prefrontal cortex. These findings suggest that the neural mechanisms used in successful self-control can be activated by exogenous attention cues, and provide insights into the processes through which behavioral therapies and public policies could facilitate self-control.