ConCerv: a prospective trial of conservative surgery for low-risk early-stage cervical cancer

ConCerv: a prospective trial of conservative surgery for low-risk early-stage cervical cancer
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DOI:
10.1136/ijgc-2021-002921
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发表时间:
2021-10-01
影响因子:
4.8
通讯作者:
Ramirez, Pedro T.
Ramirez, Pedro T.
中科院分区:
医学3区
文献类型:
--
作者:
Schmeler, Kathleen M.;Pareja, Rene;Ramirez, Pedro T.

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目的ConCerv试验的目的是前瞻性地评估保守性手术治疗早期低风险宫颈癌的可行性。方法从2010年4月至2019年3月,一项前瞻性、单臂、多中心研究评估了来自9个国家16个研究中心的参与者的保守手术。合格标准包括:(1)FIGO 2009 IA 2-IB 1期宫颈癌;(2)鳞状细胞(任何级别)或腺癌(仅1级或2级)组织学;(3)肿瘤大小
Objective The objective of the ConCerv Trial was to prospectively evaluate the feasibility of conservative surgery in women with early-stage, low-risk cervical cancer. Methods From April 2010 to March 2019, a prospective, single-arm, multicenter study evaluated conservative surgery in participants from 16 sites in nine countries. Eligibility criteria included: (1) FIGO 2009 stage IA2-IB1 cervical carcinoma; (2) squamous cell (any grade) or adenocarcinoma (grade 1 or 2 only) histology; (3) tumor size