STRUCTURALLY DISTINCT, STAGE-SPECIFIC RIBOSOMES OCCUR IN PLASMODIUM
STRUCTURALLY DISTINCT, STAGE-SPECIFIC RIBOSOMES OCCUR IN PLASMODIUM
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DOI：
10.1126/science.3672135
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发表时间：
1987-11-13
期刊：
影响因子：
56.9
通讯作者：
MCCUTCHAN, TF
中科院分区：
文献类型：
--
作者：
GUNDERSON, JH;SOGIN, ML;MCCUTCHAN, TF
伯氏疟原虫中有两个结构不同的核基因编码细胞质小亚基核糖体 RNA。来自核糖体 RNA 基因之一的稳定转录物几乎只在蚊子生命周期的那些阶段中发现。当寄生虫感染哺乳动物宿主时，第二个基因的转录物成为主要的小亚基核糖体 RNA 种类。
Two structurally distinct nuclear genes code for cytoplasmic small subunit ribosomal RNA''s in the parasite Plasmodium berghei. Stable transcripts from one of the ribosomal RNA genes are found almost exclusively in those stages of the life cycle that develop in the mosquito. When the parasite infects the mammalian host, transcripts from the second gene become the predominant small subunit ribosomal RNA species.