Relationships of Impulsivity and Subjective Response to Alcohol Use and Related Problems
Relationships of Impulsivity and Subjective Response to Alcohol Use and Related Problems
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DOI：
10.15288/jsad.2017.78.835
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发表时间：
2017-11-01
影响因子：
3.4
通讯作者：
O'Malley, Stephanie S.
中科院分区：
文献类型：
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作者：
Berey, Benjamin L.;Leeman, Robert F.;O'Malley, Stephanie S.
目的：冲动性和对酒精的主观反应是酒精使用障碍的预测因子。本研究的目的是复制和扩展先前的研究冲动和主观反应模式之间的关系。此外，冲动和初始主观反应模式进行了检查，目前大量的情节饮酒和酒精相关的问题。方法：数据是横截面的，回顾性的自我报告，从隶属于耶鲁大学酒精中毒转化神经科学中心的五项研究的基线评估中获得。在仅限于非依赖性年轻成人（n = 186）和更大、更异质的样本（n = 363）中进行了分析。在三种不同类型的模型中使用分层回归分析数据。结果：在年轻的成年人，非依赖性样本，冲动是一个统计学显着预测较低的最近镇静主观反应。冲动性和初始镇静主观反应模式是过去一年大量饮酒的统计学显著预测因素。冲动，而不是最初的主观反应模式，是一个统计学上的显着预测去年酒精相关的问题。较大样本的结果相似。结论：更多冲动的人可能感觉到酒精的镇静作用较少，这与大量饮酒有关。然而，更高水平的冲动可能比减少主观反应更负责任的决策，导致负面的饮酒后果。这些结果表明，高冲动和某些主观反应模式是值得干预的目标。
Objective: Impulsivity and subjective response to alcohol are predictors of alcohol use disorder. The purpose of this study was to replicate and extend prior research examining relationships between impulsivity and subjective response patterns. In addition, impulsivity and initial subjective response patterns were examined in relation to current heavy episodic drinking and alcohol-related problems. Method: Data were cross-sectional, retrospective self-reports, obtained from baseline assessments from five studies affiliated with the Yale Center for the Translational Neuroscience of Alcoholism. Analyses were conducted in a sample restricted to nondependent, young adults (n = 186) and in a larger, more heterogeneous sample (n = 363). Data were analyzed using hierarchical regression in three separate types of models. Results: In the young adult, nondependent sample, impulsivity was a statistically significant predictor of lower recent sedative subjective response. Impulsivity and initial sedative subjective response patterns were statistically significant predictors of past-year heavy drinking. Impulsivity, but not initial subjective response patterns, was a statistically significant predictor of past-year alcohol-related problems. Findings in the larger sample were similar. Conclusions: More-impulsive individuals may perceive less sedation from alcohol, which is associated with increased heavy drinking. However, higher levels of impulsivity may be more responsible than diminished subjective response for poor decision making that results in negative drinking consequences. These results suggest that high impulsivity and certain subjective response patterns are worthy intervention targets.