Sleep deprivation in the rat: X. Integration and discussion of the findings.
Sleep deprivation in the rat: X. Integration and discussion of the findings.
复制标题
DOI：
10.1093/sleep/12.1.68
复制
发表时间：
2002-02
期刊：
影响因子：
5.6
通讯作者：
A. Rechtschaffen;B. Bergmann;C. Everson;C. Kushida;M. Gilliland
中科院分区：
文献类型：
--
作者：
A. Rechtschaffen;B. Bergmann;C. Everson;C. Kushida;M. Gilliland
本文对大鼠全面睡眠剥夺和选择性睡眠剥夺的一系列研究结果进行了综合和讨论。这些研究表明，完全睡眠剥夺、矛盾睡眠剥夺和非快速眼动（NREM）睡眠中断和/或剥夺会产生一种可靠的综合征，包括死亡、外表虚弱、皮肤损伤、食物摄入量增加、体重减轻、能量消耗增加、剥夺后期体温下降、血浆去甲肾上腺素增加和血浆甲状腺素减少。这种综合征对睡眠功能的意义尚不完全清楚，但一些变化表明，睡眠可能是有效调节体温的必要条件。
The results of a series of studies on total and selective sleep deprivation in the rat are integrated and discussed. These studies showed that total sleep deprivation, paradoxical sleep deprivation, and disruption and/or deprivation of non-rapid eye movement (NREM) sleep produced a reliable syndrome that included death, debilitated appearance, skin lesions, increased food intake, weight loss, increased energy expenditure, decreased body temperature during the late stages of deprivation, increased plasma norepinephrine, and decreased plasma thyroxine. The significance of this syndrome for the function of sleep is not entirely clear, but several changes suggested that sleep may be necessary for effective thermoregulation.