Increased resistance in the pneumococcus.
Increased resistance in the pneumococcus.
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肺炎球菌的抵抗力增加。
DOI：
10.1056/nejm197101282840411
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发表时间：
1971
期刊：
影响因子：
--
通讯作者：
M. Finland
中科院分区：
文献类型：
--
作者：
M. Finland
对抗菌剂感兴趣的微生物学家和被要求治疗细菌感染患者的医生已经习惯于期待对任何新引入的、高度活性和有用的抗生素产生耐药性。越来越多的金黄色葡萄球菌、结核分枝杆菌和最近的革兰氏阴性杆菌的耐药菌株已经被注意到。对青霉素(青霉素或青霉素G)产生抗药性的葡萄球菌在这种抗生素首次使用后很早就被发现，但这种现象造成的问题只有在密集使用这种药物几年后才变得明显。同样，尽管…
Microbiologists who are interested in antimicrobial agents and physicians who are called upon to treat patients with bacterial infections have become accustomed to expect resistance to develop or emerge against any newly introduced, highly active and useful antibiotic. Increasing numbers of resistant strains of Staphylococcus aureus, Mycobacterium tuberculosis and, more recently, gram-negative bacilli have been noted. Staphylococci resistant to penicillin (benzyl-penicillin or penicillin G) were noted early after this antibiotic first came into use, but the full extent of the problem created by this phenomenon became apparent only after a few years of intensive use of this agent. Likewise, although . . .