ANATOMICAL SEGREGATION OF 2 CORTICAL VISUAL PATHWAYS IN THE MACAQUE MONKEY
ANATOMICAL SEGREGATION OF 2 CORTICAL VISUAL PATHWAYS IN THE MACAQUE MONKEY
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DOI：
10.1017/s0952523800005769
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发表时间：
1990-06-01
影响因子：
1.9
通讯作者：
BULLIER, J
中科院分区：
文献类型：
--
作者：
MOREL, A;BULLIER, J
许多证据表明，在猕猴中，下顶叶和下颞叶皮质处理不同类型的视觉信息。有人认为，视觉信息到达这两个分区遵循单独的途径，从纹状皮层通过前纹状皮层。我们通过在下顶叶和下颞叶皮层注射逆行荧光示踪剂，即固蓝和二脒基黄，并在二维重建的皮层中检查含有标记细胞的皮层区域的空间模式，直接检查了这种可能性。在下颞叶皮层注射的结果表明，TEO接受来自V2区、腹侧V3区、V3A区、中央V4区、V4t区、DPL在纹前皮质和上级颞沟（STS）的IPa、PGa和FST区。TEp区只接受来自纹前皮质V4和STS前部IPa、PGa和FST的传入。TEa区不接受纹前传入，受STS前部的IPa、PGa、FST和TPO的支配，下顶叶皮层注射的结果表明，POa区接受纹前皮层的背侧V3、V3A、外周V4、DPL和PO的传入，STS前部的MST和 *VIP的传入以及IPa、PGa、TPO和FST的传入。PGC区（相当于7a区）由PO、MST和STS前部的TPO支配。在POa区和TEO区联合注射固蓝和二脒基黄后对标记图案的二维重建检查显示，这些区域主要由不同的纹前区支配。只有一个小区域，以区域V3A为中心，延伸到V4和DPL，含有两种注射标记的细胞以及少量双标记细胞。相反，POa和TEO区接受来自STS前部IPa、PGa和FST.These结果直接表明，视觉信息从纹状体皮质到达下顶叶和下颞叶皮质，主要是通过独立的前纹状体皮质通路。另一方面，顶叶和下颞叶皮层接收来自前STS的广泛区域的共同输入，这可能在连接视觉系统的这两个皮层分区中发生的处理中发挥作用。
A number of lines of evidence suggest that, in the macaque monkey, inferior parietal and inferotemporal cortices process different types of visual information. It has been suggested that visual information reaching these two subdivisions follows separate pathways from the striate cortex through the prestriate cortex. We examined directly this possibility by placing injections of the retrograde fluorescent tracers, fast blue and diamidino yellow, in inferior parietal and inferotemporal cortex and examining the spatial pattern of cortical areas containing labeled cells in two-dimensional reconstructions of the cortex.The results of injections in inferotemporal cortex show that TEO receives afferents from areas V2, ventral V3, V3A, central V4, V4t, and DPL in prestriate cortex and from areas IPa, PGa, and FST in the superior temporal sulcus (STS). Area TEp receives afferents only from V4 in prestriate cortex and from IPa, PGa, and FST in the anterior STS. Area TEa receives no prestriate input and is innervated by IPa, PGa, FST, and TPO in the anterior STS.The results of injections in inferior parietal cortex demonstrate that POa receives afferents from dorsal V3, V3A, peripheral V4, DPL, and PO in prestriate cortex, from MST and *VIP and from IPa, PGa, TPO, and FST in anterior STS. Area PGc (corresponding to 7a) is innervated by PO, MST, and by TPO in the anterior STS.Examination of the two-dimensional reconstructions of the pattern of labeling after combined injections of fast blue and diamidino yellow in areas POa and TEO revealed that these areas are principally innervated by different prestriate areas. Only a small region, centered on area V3A and extending into V4 and DPL, contained cells labeled by either injection as well as a small number of double-labeled cells. In contrast, areas POa and TEO receive afferents from extensive common regions in the anterior STS corresponding to areas IPa, PGa, and FST.These results directly demonstrate that visual information from the striate cortex reaches inferior parietal and inferotemporal cortices through largely separate prestriate cortical pathways. On the other hand, both parietal and inferotemporal cortices receive common inputs from extensive regions in the anterior STS which may play a role in linking the processing occurring in these two cortical subdivisions of the visual system.