British HIV Association guidelines for the management of HIV in pregnancy and postpartum 2018
British HIV Association guidelines for the management of HIV in pregnancy and postpartum 2018
复制标题
DOI：
10.1111/hiv.12720
复制
发表时间：
2019-03-01
期刊：
影响因子：
3
通讯作者：
Wright, Alison
中科院分区：
文献类型：
--
作者：
Gilleece, Yvonne;Tariq, Shema;Wright, Alison
怀孕和产后管理艾滋病毒的一个关键目标是优化女性自身的健康。此外，在管理艾滋病毒感染者方面取得的主要成功之一是预防了艾滋病毒的垂直传播。随着常规产前艾滋病毒筛查的广泛实施，垂直传播现在在英国很少发生。尽管最近很少有随机对照试验在妊娠或产科干预中使用抗逆转录病毒疗法，但实践仍在不断发展。这在很大程度上是由观察数据、理论考虑和专家意见提供的。一开始，编写小组的目标是使这些指南尽可能与临床相关和实用。编写小组起草了一份反映日常做法和疑问的问题清单。与会者承认，其中许多主题的证据水平很差，但认识到需要提供指导。这些准则扩大到与怀孕和产后期间艾滋病毒管理有关的所有领域。该准则旨在告知和帮助保健工作者在艾滋病毒感染情况下进行妊娠管理。这些建议并不具有规范性或限制性，而且人们认识到，可能会出现最佳管理可能偏离这些建议的情况，并且会出现新的数据，以更好地为实践提供信息。我们认识到，少数跨性别和非二元性别的艾滋病毒感染者也会怀孕。为了简洁起见，我们在这些指南中使用“女性”或“女性”一词，前提是指导也适用于跨性别和非二元个体。
A key goal of managing HIV in pregnancy and postpartum is to optimise a woman’s own health. Furthermore, one of the major successes in the management of individuals living with HIV has been the prevention of vertical transmission of HIV. With the widespread implementation of routine antenatal screening for HIV, vertical transmission is now a rare occurrence in the UK. Despite few recent randomised controlled trials of the use of ART in pregnancy or obstetric intervention, practice continues to evolve. This is largely informed by observational data, theoretical considerations and expert opinion.At the outset, the aim of the writing group was to make these guidelines as clinically relevant and as practical as possible. The writing group drew up a list of questions reflecting day-to-day practice and queries. It was acknowledged that the level of evidence for many of these topics was poor but recognised that there was a need to provide guidance. These guidelines have expanded on all areas relevant to the management of HIV in pregnancy and the postpartum period. The guidelines are intended to inform and aid healthcare workers in the management of pregnancy in the context of HIV. They are not intended to be prescriptive or restrictive and it is recognised that situations will arise where the optimum management may deviate from these recommendations and new data will emerge to better inform practice. We recognise that a small number of trans and non-binary people living with HIV will also experience pregnancy. We use the term ‘woman’or ‘women’in these guidelines for brevity, on the understanding that guidance also applies to trans and non-binary individuals.