What do we know about chronic kidney disease in India: first report of the Indian CKD registry.
What do we know about chronic kidney disease in India: first report of the Indian CKD registry.
复制标题
DOI：
10.1186/1471-2369-13-10
复制
发表时间：
2012-03-06
期刊：
影响因子：
2.3
通讯作者：
Jha V
中科院分区：
文献类型：
--
作者：
Rajapurkar MM;John GT;Kirpalani AL;Abraham G;Agarwal SK;Almeida AF;Gang S;Gupta A;Modi G;Pahari D;Pisharody R;Prakash J;Raman A;Rana DS;Sharma RK;Sahoo RN;Sakhuja V;Tatapudi RR;Jha V
印度没有关于慢性肾脏病 (CKD) 严重程度和模式的全国数据。印度 CKD 登记记录了人口统计、病因谱、实践模式、变化和特殊特征。根据预定标准以标准化格式收集本横断面研究的数据。在52,273名成年患者中，来自南区、北区、西区和东区的患者分别占35.5%、27.9%、25.6%和11%。平均年龄为 50.1 ± 14.6 岁，男：女比例为 70：30。北区患者年龄较小，东区患者年龄较大。糖尿病肾病是最常见的原因（31%），其次是病因不明的慢性肾病（16%）、慢性肾小球肾炎（14%）和高血压肾硬化（13%）。约 48% 的病例处于第五阶段；他们比第三至第四阶段的人年轻。糖尿病肾病患者年龄较大，更有可能出现慢性肾病早期阶段，且男性比例较高；而患有不明原因 CKD 的患者更年轻，女性更多，且更常见于第五期。低收入群体的患者就诊时患有更晚期的 CKD。到公立医院就诊的患者较贫穷、较年轻，且更常患有病因不明的 CKD。该报告证实糖尿病肾病是印度的首要原因。病因不明的 CKD 患者更年轻、更贫穷，并且更有可能出现晚期 CKD。存在一些地理差异。
There are no national data on the magnitude and pattern of chronic kidney disease (CKD) in India. The Indian CKD Registry documents the demographics, etiological spectrum, practice patterns, variations and special characteristics. Data was collected for this cross-sectional study in a standardized format according to predetermined criteria. Of the 52,273 adult patients, 35.5%, 27.9%, 25.6% and 11% patients came from South, North, West and East zones respectively. The mean age was 50.1 ± 14.6 years, with M:F ratio of 70:30. Patients from North Zone were younger and those from the East Zone older. Diabetic nephropathy was the commonest cause (31%), followed by CKD of undetermined etiology (16%), chronic glomerulonephritis (14%) and hypertensive nephrosclerosis (13%). About 48% cases presented in Stage V; they were younger than those in Stages III-IV. Diabetic nephropathy patients were older, more likely to present in earlier stages of CKD and had a higher frequency of males; whereas those with CKD of unexplained etiology were younger, had more females and more frequently presented in Stage V. Patients in lower income groups had more advanced CKD at presentation. Patients presenting to public sector hospitals were poorer, younger, and more frequently had CKD of unknown etiology. This report confirms the emergence of diabetic nephropathy as the pre-eminent cause in India. Patients with CKD of unknown etiology are younger, poorer and more likely to present with advanced CKD. There were some geographic variations.