Repellency of novel catnip (Nepeta cataria) cultivar extracts against Ixodes scapularis and Haemaphysalis longicornis (Acari: Ixodida: Ixodidae)
Repellency of novel catnip (Nepeta cataria) cultivar extracts against Ixodes scapularis and Haemaphysalis longicornis (Acari: Ixodida: Ixodidae)
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DOI：
10.1016/j.ttbdis.2022.102046
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发表时间：
2022-09-18
影响因子：
3.2
通讯作者：
Toledo, Alvaro
中科院分区：
文献类型：
--
作者：
Gonzalez, Julia;Lockhart, Anthony;Toledo, Alvaro
由于许多蜱类在传播人类病原体方面具有媒介作用，因此蜱叮咬是一个主要的公共卫生问题。合成驱蚊剂，如n -二乙基-间甲苯酰胺（避蚊胺）仍然是驱蚊的标准。尽管如此，仍然需要与避蚊胺性能相似或更好的天然商业替代品。研究了新开发的猫薄荷品种提取液CR3和CR9对肩胛硬蜱和长角血蜱的驱避效果。体外剂量-反应试验表明，CR3和CR9提取物与避蚊胺具有相似的驱避性能。在20%浓度下，CR3和CR9提取物的驱避率均为100%。猫薄荷提取物保持其驱避特性至少8小时。在两种选择的实验中，肩胛骨夜蛾对CR3比避蚊胺更敏感，而长角夜蛾则没有。此外，CR3能缩短肩胛骨蜱的寿命，提示其对蜱有杀螨作用。综上所述，CR3和CR9猫薄荷提取物是很有前景的驱蜱剂，应进一步开发，单独或与其他驱蜱剂联合使用，并测试其作为人类驱蜱剂的使用。
Tick bites are a major public health concern due to the vector role that many tick species have in transmitting human pathogens. Synthetic repellents such as N-diethyl-meta-toluamide (DEET) remain the standard for repellency. Still, there is a need for natural commercial alternatives with similar or better properties than DEET. We evaluated the repellency of two extracts, CR3 and CR9, derived for newly developed catnip cultivars on two tick species, Ixodes scapularis and Haemaphysalis longicornis. Dose-response in vitro assays showed that CR3 and CR9 extracts have similar repellency properties to DEET. At a 20% concentration, both CR3 and CR9 extracts exhibited a repellency of 100%. Catnip extracts maintained their repellency properties for at least 8 h. In a two -choice assay, I. scapularis, but not H. longicornis, was more sensitive to CR3 than DEET. In addition, CR3 reduces the life span of I. scapularis, suggesting that it has an acaricidal effect on ticks. In summary, CR3 and CR9 catnip extracts are promising tick repellents that should be further developed, alone or in combination with other tick repellents, and tested for their use as tick repellents for humans.