Enantio‐ and Diastereoselective Hydrogenation via Dynamic Kinetic Resolution by a Cationic Iridium Complex in the Synthesis of β‐Hydroxy‐α‐amino Acid Esters.
Enantio‐ and Diastereoselective Hydrogenation via Dynamic Kinetic Resolution by a Cationic Iridium Complex in the Synthesis of β‐Hydroxy‐α‐amino Acid Esters.
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DOI：
10.1002/chin.200703079
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发表时间：
2006-09
期刊：
影响因子：
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通讯作者：
K. Makino;Masamichi Iwasaki;Y. Hamada
中科院分区：
文献类型：
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作者：
K. Makino;Masamichi Iwasaki;Y. Hamada
以四[3，5-二（三氟甲基）苯基]硼酸盐（BARF）为配体，合成了一种易操作的铱配合物，实现了α-氨基-β-酮酯在低氢压下的反选择不对称氢化反应.
Anti-selective asymmetric hydrogenation of α-amino-β-keto esters via dynamic kinetic resolution under low hydrogen pressure has been achieved by an easily-handled cationic iridium complex with tetrakis[3,5-bis(trifluoromethyl)phenyl]borate (BARF) as a counterion.