A Neural Marker of Speech Intention: Evidence From Contingent Negative Variation.
A Neural Marker of Speech Intention: Evidence From Contingent Negative Variation.
复制标题
言语意图的神经标记：来自偶然负变化的证据。
DOI：
10.1044/2020_jslhr-20-00277
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Marsh,BriannaM
中科院分区：
文献类型：
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作者：
Kidwai,Juhi;Brumberg,JonathanS;Marsh,BriannaM
目的探讨说话前脑活动的变化是否可以作为言语意图的神经标记。具体来说，在三种不同的研究设计中，研究了语音产生之前的偶然负变异（CNV）的变化，以确定在说话任务中最大化信号检测的方法。方法采用三种不同的实验方案收集脑电数据，在不同的时间和语言信息类型下引出口语单词任务中的CNV。第一种方案在指示参与者是否说话之前先提供要说的单词，第二种方案同时提供单词和说话指令，第三种方案在单词之前提供说话指令。参与者（N= 18）被分成三组（每个协议一组），并被指示根据任务指示说出（Go）或不说出（NoGo）每个单词。CNV是通过分析Go和NoGo试验的斜率差异来测量的。结果：半球偏侧对CNV斜率的统计显著影响证实了第三种方案，即参与者知道他们会提前说出单词，作为可靠地引发与言语意图相关的CNV反应的范式。结论：当指令在单词之前已知时，最大的CNV反应表明，该协议测量的神经处理可能反映了一个广义的语音意图过程，在这个过程中，语音语言系统准备说话，然后在提供单词信息后执行生产。本研究确定的最佳协议的进一步分析需要额外的实验调查，以确认其在引发言语意图的客观标记中的作用。补充Materialhttps: / / doi.org/10.23641/asha.14111468
PurposeThis study investigated whether changes in brain activity preceding spoken words can be used as a neural marker of speech intention. Specifically, changes in the contingent negative variation (CNV) were examined prior to speech production in three different study designs to determine a method that maximizes signal detection in a speaking task.MethodElectroencephalography data were collected in three different protocols to elicit the CNV in a spoken word task that varied the timing and type of linguistic information. The first protocol provided participants with the word to be spoken before the instruction of whether or not to speak, the second provided both the word and the instruction to speak, and the third provided the instruction to speak before the word. Participants (N= 18) were split into three groups (one for each protocol) and were instructed to either speak (Go) or refrain from speaking (NoGo) each word according to task instructions. The CNV was measured by analyzing the difference in slope between Go and NoGo trials.ResultsStatistically significant effects of hemispheric laterality on the CNV slope confirm the third protocol where the participants know they will speak in advance of the word, as the paradigm that reliably elicits a CNV response related to speech intention.ConclusionsThe maximal CNV response when the instruction is known before the word indicates the neural processing measured in this protocol may reflect a generalized speech intention process in which the speech-language systems become prepared to speak and then execute production once the word information is provided. Further analysis of the optimal protocol identified in this study requires additional experimental investigation to confirm its role in eliciting an objective marker of speech intention.Supplemental Materialhttps://doi.org/10.23641/asha.14111468