Facial recognition deficits and cognition in schizophrenia
Facial recognition deficits and cognition in schizophrenia
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DOI：
10.1016/s0920-9964(03)00131-2
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发表时间：
2004-05-01
影响因子：
4.5
通讯作者：
Katschnig, H
中科院分区：
文献类型：
--
作者：
Sachs, G;Steger-Wuchse, D;Katschnig, H
先前的研究发现精神分裂症患者的面部情感和认知识别受损。我们比较了精神分裂症患者和健康对照志愿者在情绪识别的计算机任务，以确定情绪处理缺陷是否与神经认知性能。对40名患者（25名男性，15名女性，平均年龄+/- S.D.）进行计算机神经心理测试组合（CNP）。30.4+/- 8.1）的精神分裂症患者（DSM-IV，15例首发和25例慢性病患者）和43名健康志愿者。使用了德国版的PENN面部辨别、区分和记忆测试，包括快乐、悲伤和中性的面孔。此外，所有患者都接受了标准神经心理电池测试，并对阳性和阴性症状进行了评级。精神分裂症患者在所有情绪识别任务上的表现均低于对照组（p < 0.01）。我们发现，对快乐（p < 0.02）和快乐女性面孔（p < 0.01）的情感辨别，对悲伤与快乐面孔（p < 0.001）的辨别以及对面部记忆（p < 0.04）的辨别的错误率较高。情绪辨别和面孔记忆的成绩与阴性症状的严重程度、抽象-灵活性（p < 0.001）、言语记忆（p < 0.01）和语言加工（p < 0.001）相关。这项研究并没有揭示精神分裂症患者在情感识别方面的具体缺陷。这些发现支持了这样一种观点，即精神分裂症患者的情绪识别困难与关键的认知缺陷有关。(C)2003 Elsevier B. V.保留所有权利。
Previous investigations have found impaired recognition of facial affect and cognition in schizophrenia. We compared patients with schizophrenia and healthy control volunteers on computerized tasks of emotion recognition, to determine whether emotion processing deficits were correlated with neurocognitive performance. A Computerized Neuropsychological Test Battery (CNP) was administered to 40 patients (25 male, 15 female, mean age +/- S.D. 30.4 +/- 8.1) with schizophrenia (DSM-IV, 15 first episode and 25 chronically ill patients) treated with atypical neuroleptics and 43 healthy volunteers. A German version of the PENN Facial Discrimination, Differentiation and Memory Test, including happy, sad and neutral faces was used. Additionally, all patients were tested with a standard neuropsychological battery and were rated for positive and negative symptoms. Patients with schizophrenia performed worse than control subjects on all emotion recognition tasks (p < 0.01). We found higher error rates for discrimination of emotion in happy (p < 0.02) and happy female faces (p < 0.01), for differentiation of sad versus happy faces (p < 0.001) and for facial memory (p < 0.04). Poorer performance in emotion discrimination and facial memory correlated with severity of negative symptoms, abstraction-flexibility (p < 0.001), verbal memory (p < 0.01) and language processing (p < 0.001). The study did not reveal a specific deficit for emotion recognition in schizophrenia. These findings lend support to the notion that difficulties in emotion recognition are associated in schizophrenia with key cognitive deficits. (C) 2003 Elsevier B.V. All rights reserved.